380430-54-6
(2-Aminocarbonylphenyl)boronic acid
CAS: 380430-54-6
Molecular Formula: C7H8BNO3
380430-54-6 - Names and Identifiers
380430-54-6 - Physico-chemical Properties
| Molecular Formula | C7H8BNO3 |
| Molar Mass | 164.95 |
| Density | 1.32±0.1 g/cm3(Predicted) |
| Melting Point | 226-230°C |
| Boling Point | 410.3±47.0 °C(Predicted) |
| Flash Point | 201.9°C |
| Vapor Presure | 1.81E-07mmHg at 25°C |
| pKa | 8.21±0.53(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.585 |
380430-54-6 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29319090 |
| Hazard Note | Corrosive |
380430-54-6 - Introduction
(2-Aminocarbonylphenyl)boronic acid is an organic compound with the chemical formula C7H8BNO3.
Nature:
(2-Aminocarbonylphenyl)boronic acid is a white crystalline solid with a melting point of approximately 220-225°C. It has good solubility and can be dissolved in water, ethanol and organic solvents.
Use:
(2-Aminocarbonylphenyl)boronic acid is an important organic synthesis intermediate, commonly used in organic synthesis reactions. It can be used to construct aromatic ring structures and participate in the reduction and hydroxylation reactions of aldehyde or ketone compounds. In addition, it can also be used as a metal-assisted coupling reagent to participate in the coupling reaction of phenyl sulfonate.
Preparation Method:
(2-Aminocarbonylphenyl) There are two main methods for the preparation of boronic acid. One is the reaction of phenylboronic acid with formylamino bromomethane to generate the target product; the other is obtained by the reaction of phenylboronic acid with methyl formate under the catalysis of agarose.
Safety Information:
(2-Aminocarbonylphenyl) The safety of boronic acid has not been fully evaluated, so necessary safety measures should be taken when using it. It may cause irritation to the eyes, skin and respiratory system and direct contact should be avoided. Wear appropriate personal protective equipment, including glasses, gloves and lab clothes. At the same time, it should also be operated in a well-ventilated place to avoid inhaling its vapor.
Nature:
(2-Aminocarbonylphenyl)boronic acid is a white crystalline solid with a melting point of approximately 220-225°C. It has good solubility and can be dissolved in water, ethanol and organic solvents.
Use:
(2-Aminocarbonylphenyl)boronic acid is an important organic synthesis intermediate, commonly used in organic synthesis reactions. It can be used to construct aromatic ring structures and participate in the reduction and hydroxylation reactions of aldehyde or ketone compounds. In addition, it can also be used as a metal-assisted coupling reagent to participate in the coupling reaction of phenyl sulfonate.
Preparation Method:
(2-Aminocarbonylphenyl) There are two main methods for the preparation of boronic acid. One is the reaction of phenylboronic acid with formylamino bromomethane to generate the target product; the other is obtained by the reaction of phenylboronic acid with methyl formate under the catalysis of agarose.
Safety Information:
(2-Aminocarbonylphenyl) The safety of boronic acid has not been fully evaluated, so necessary safety measures should be taken when using it. It may cause irritation to the eyes, skin and respiratory system and direct contact should be avoided. Wear appropriate personal protective equipment, including glasses, gloves and lab clothes. At the same time, it should also be operated in a well-ventilated place to avoid inhaling its vapor.
Last Update：2024-04-10 22:29:15
