381248-06-2 - Names and Identifiers
381248-06-2 - Physico-chemical Properties
Molecular Formula | C16H11BrN2O
|
Molar Mass | 327.18 |
Density | 1.539±0.06 g/cm3(Predicted) |
Melting Point | 79-81°C |
Boling Point | 461.7±45.0 °C(Predicted) |
Solubility | Chloroform (Slightly), DMSO (Slightly) |
Appearance | Solid |
Color | Light Brown to Brown |
pKa | 4.73±0.19(Predicted) |
Storage Condition | 2-8°C |
Stability | Light Sensitive |
Sensitive | IRRITANT |
MDL | MFCD21607392 |
381248-06-2 - Introduction
5-bromo-1-phenyl-[2 ',3-Bipyridin]-6(1H)-one is an organic compound with the chemical formula C16H10BrN2O.
Its properties are as follows:
-Appearance: colorless crystal or white powder
-melting point: about 150-155 ℃
-Solubility: insoluble in water, insoluble in general organic solvents, soluble in benzene and chlorinated alkanes.
5-bromo-1-phenyl-[2 ',3-Bipyridin]-6(1H)-one has the following main uses:
-As a catalyst or raw material in organic synthesis reactions, it can participate in C- C bond formation reactions, such as Suzuki coupling reaction and Stille coupling reaction.
-In the field of chemical drugs, it can be used to synthesize biologically active compounds, such as anti-cancer drugs.
-In the field of dyes, it can be used to synthesize dye molecules.
Method for preparing 5-bromo-1-phenyl-[2 ',3-Bipyridin]-6(1H)-one:
It can be obtained by reacting 2,3-bipyridinecarboxaldehyde with phenylboronic acid or phenylethyl alcohol and hydrochloric acid.
Regarding safety information, according to current information, 5-bromo-1-phenyl-[2 ',3-Bipyridin]-6(1H)-one is relatively safe under reasonable use. However, as a chemical substance, pay attention to follow the operating specifications of the chemical laboratory and avoid contact with skin, eyes and respiratory tract. In case of accidental exposure or discomfort, seek medical attention immediately.
Last Update:2024-04-09 20:02:46