4,4,5,5-TetraMethyl-2-(2-thienyl)-1,3,2-dioxaborolane

4,4,5,5-TetraMethyl-2-(2-thienyl)-1,3,2-dioxaborolane - Names and Identifiers

Name	2-Thiopheneboronic acid pinacol ester
Synonyms	2-Thiopheneboronic acid pinacol ester 2-THIOPHENEBORONIC ACID PINACOL ESTER Thiophene-2-boronic acid pinacol ester THIOPHENE-2-BORONIC ACID, PINACOL ESTER 4,4,5,5-TetraMethyl-2-(2-thienyl)-1,3,2-dioxaborolane 4,4,5,5-Tetramethyl-2-(thien-2-yl)-1,3,2-dioxaborolane 4,4,5,5-tetramethyl-2-thiophen-2-yl-1,3,2-dioxaborolane 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)THIOPHENE 4,4,5,5-Tetramethyl-2-(Thiophen-2-Yl)-1,3,2-Dioxaborolane 4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane 2-(thiophene-2-yl)-4,4,5,5-tetraMethyl-[1,3,2]dioxaborolane Thiophene-2-boronic acid pinacol ester 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene
CAS	193978-23-3
InChI	InChI=1/C10H15BO2S/c1-9(2)10(3,4)13-11(12-9)8-6-5-7-14-8/h5-7H,1-4H3

4,4,5,5-TetraMethyl-2-(2-thienyl)-1,3,2-dioxaborolane - Physico-chemical Properties

Molecular Formula	C10H15BO2S
Molar Mass	210.1
Density	1.07±0.1 g/cm3(Predicted)
Melting Point	68-70°C
Boling Point	286.5±13.0 °C(Predicted)
Flash Point	127.099°C
Vapor Presure	0.005mmHg at 25°C
Appearance	Solid
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.501
MDL	MFCD05663878

4,4,5,5-TetraMethyl-2-(2-thienyl)-1,3,2-dioxaborolane - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R25 - Toxic if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN2811
WGK Germany	3

4,4,5,5-TetraMethyl-2-(2-thienyl)-1,3,2-dioxaborolane - Introduction

2-Thiopheneboronic acid pinacol ester is an organic compound with the chemical formula C8H5BO2S. It is a colorless to light yellow crystal, soluble in many organic solvents.

2-Thiopheneboronic acid pinacol ester has many applications, the most important of which is as a catalyst in organic synthesis. It can be used to catalyze hydrogenation, reduction, oxidation, nucleophilic substitution and other reactions, and has the advantages of high efficiency, environmental protection and multi-function.

The preparation of 2-Thiopheneboronic acid pinacol ester can usually be completed by the condensation reaction of Phenylboronic acid and 2-bromothiophene. Under the reaction conditions, by controlling the temperature, solvent, catalyst and reaction time and other factors, a higher yield of the product can be obtained.

When using 2-Thiopheneboronic acid pinacol ester, you should pay attention to some security issues. It has a certain irritation, contact with the skin may cause inflammation and allergic reactions. During use, protective gloves, goggles and protective clothing should be worn to avoid contact with skin and inhalation of gas. In addition, 2-Thiopheneboronic acid pinacol ester should be stored in a dry, cool place, avoid contact with oxygen, water and strong oxidants.

In General, 2-Thiopheneboronic acid pinacol ester is an important organic synthesis catalyst with a wide range of application prospects. Pay attention to safety and follow the correct operation method when using it.

Last Update：2024-04-10 22:29:15