4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane - Names and Identifiers
Name | 2-Thiopheneboronic acid pinacol ester
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Synonyms | 2-Thiopheneboronic acid pinacol ester 2-THIOPHENEBORONIC ACID PINACOL ESTER Thiophene-2-boronic acid pinacol ester THIOPHENE-2-BORONIC ACID, PINACOL ESTER 4,4,5,5-TetraMethyl-2-(2-thienyl)-1,3,2-dioxaborolane 4,4,5,5-Tetramethyl-2-(thien-2-yl)-1,3,2-dioxaborolane 4,4,5,5-tetramethyl-2-thiophen-2-yl-1,3,2-dioxaborolane 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)THIOPHENE 4,4,5,5-Tetramethyl-2-(Thiophen-2-Yl)-1,3,2-Dioxaborolane 4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane 2-(thiophene-2-yl)-4,4,5,5-tetraMethyl-[1,3,2]dioxaborolane Thiophene-2-boronic acid pinacol ester
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene
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CAS | 193978-23-3
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InChI | InChI=1/C10H15BO2S/c1-9(2)10(3,4)13-11(12-9)8-6-5-7-14-8/h5-7H,1-4H3 |
4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane - Physico-chemical Properties
Molecular Formula | C10H15BO2S
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Molar Mass | 210.1 |
Density | 1.07±0.1 g/cm3(Predicted) |
Melting Point | 68-70°C |
Boling Point | 286.5±13.0 °C(Predicted) |
Flash Point | 127.099°C |
Vapor Presure | 0.005mmHg at 25°C |
Appearance | Solid |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.501 |
MDL | MFCD05663878 |
4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane - Risk and Safety
Hazard Symbols | T - Toxic
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Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R25 - Toxic if swallowed
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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UN IDs | UN2811 |
WGK Germany | 3 |
4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane - Introduction
2-Thiopheneboronic acid pinacol ester is an organic compound with the chemical formula C8H5BO2S. It is a colorless to light yellow crystal, soluble in many organic solvents.
2-Thiopheneboronic acid pinacol ester has many applications, the most important of which is as a catalyst in organic synthesis. It can be used to catalyze hydrogenation, reduction, oxidation, nucleophilic substitution and other reactions, and has the advantages of high efficiency, environmental protection and multi-function.
The preparation of 2-Thiopheneboronic acid pinacol ester can usually be completed by the condensation reaction of Phenylboronic acid and 2-bromothiophene. Under the reaction conditions, by controlling the temperature, solvent, catalyst and reaction time and other factors, a higher yield of the product can be obtained.
When using 2-Thiopheneboronic acid pinacol ester, you should pay attention to some security issues. It has a certain irritation, contact with the skin may cause inflammation and allergic reactions. During use, protective gloves, goggles and protective clothing should be worn to avoid contact with skin and inhalation of gas. In addition, 2-Thiopheneboronic acid pinacol ester should be stored in a dry, cool place, avoid contact with oxygen, water and strong oxidants.
In General, 2-Thiopheneboronic acid pinacol ester is an important organic synthesis catalyst with a wide range of application prospects. Pay attention to safety and follow the correct operation method when using it.
Last Update:2024-04-10 22:29:15