4,4,5,5-Tetramethyl-2-(4-methylbenzyl)

4,4,5,5-Tetramethyl-2-(4-methylbenzyl) - Names and Identifiers

Name	4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane
Synonyms	4,4,5,5-Tetramethyl-2-(4-methylbenzyl) 4-Methylbenzylboronic acid pinacol ester 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane 4,4,5,5-tetramethyl-2-[(4-methylphenyl)methyl]-1,3,2-dioxaborolane 1,3,2-Dioxaborolane, 4,4,5,5-tetraMethyl-2-[(4-Methylphenyl)Methyl]-
CAS	356570-52-0
InChI	InChI=1/C14H21BO2/c1-11-6-8-12(9-7-11)10-15-16-13(2,3)14(4,5)17-15/h6-9H,10H2,1-5H3

4,4,5,5-Tetramethyl-2-(4-methylbenzyl) - Physico-chemical Properties

Molecular Formula	C14H21BO2
Molar Mass	232.13
Density	0.953 g/mL at 25 °C
Boling Point	95 °C/1 mmHg
Flash Point	110°C
Vapor Presure	0.00378mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	n20/D 1.489

4,4,5,5-Tetramethyl-2-(4-methylbenzyl) - Risk and Safety

WGK Germany

4,4,5,5-Tetramethyl-2-(4-methylbenzyl) - Introduction

4,4, 5,5-tetraethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane(4,4, 5,5-tetraethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane) is an organic boron compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Molecular formula: C16H22BO2
-Molecular weight: 262.16g/mol
-Boiling point: about 180-190°C
-Density: about 1.004 g/mL
-Solubility: Soluble in common organic solvents such as ethanol, dimethylformamide
-Stability: Stable under dry and anhydrous conditions

Use:
- 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane can be used as an organoboron reagent in organic synthesis for benzylation, coupling reaction, reduction reaction, etc.
-It can participate in C- C bond-forming reactions for the synthesis of natural products, drugs and organic compounds.

Preparation Method:
It can react with benzyl boronic acid and methallyl lithium to produce benzyl lithium, and then react with alkyl boron chloride to obtain 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane.

Safety Information:
- 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane may be irritating to the skin, eyes, and respiratory tract and contact should be avoided.
-Good laboratory practices should be followed during use, and appropriate personal protective equipment should be worn to ensure good ventilation.
-Should be stored in a dry, cool place, away from direct sunlight and high temperature.
-When handling this compound, use appropriate waste disposal methods and comply with local environmental regulations.

Last Update：2024-04-09 02:00:45