4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane - Names and Identifiers
Name | 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane
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Synonyms | 4,4,5,5-Tetramethyl-2-(4-methylbenzyl) 4-Methylbenzylboronic acid pinacol ester 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane 4,4,5,5-tetramethyl-2-[(4-methylphenyl)methyl]-1,3,2-dioxaborolane 1,3,2-Dioxaborolane, 4,4,5,5-tetraMethyl-2-[(4-Methylphenyl)Methyl]-
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CAS | 356570-52-0
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InChI | InChI=1/C14H21BO2/c1-11-6-8-12(9-7-11)10-15-16-13(2,3)14(4,5)17-15/h6-9H,10H2,1-5H3 |
4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane - Physico-chemical Properties
Molecular Formula | C14H21BO2
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Molar Mass | 232.13 |
Density | 0.953 g/mL at 25 °C |
Boling Point | 95 °C/1 mmHg |
Flash Point | 110°C |
Vapor Presure | 0.00378mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.489 |
4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane - Risk and Safety
4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane - Introduction
4,4, 5,5-tetraethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane(4,4, 5,5-tetraethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane) is an organic boron compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C16H22BO2
-Molecular weight: 262.16g/mol
-Boiling point: about 180-190°C
-Density: about 1.004 g/mL
-Solubility: Soluble in common organic solvents such as ethanol, dimethylformamide
-Stability: Stable under dry and anhydrous conditions
Use:
- 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane can be used as an organoboron reagent in organic synthesis for benzylation, coupling reaction, reduction reaction, etc.
-It can participate in C- C bond-forming reactions for the synthesis of natural products, drugs and organic compounds.
Preparation Method:
It can react with benzyl boronic acid and methallyl lithium to produce benzyl lithium, and then react with alkyl boron chloride to obtain 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane.
Safety Information:
- 4,4,5,5-tetramethyl-2-(4-methylbenzyl)-1,3,2-dioxaborolane may be irritating to the skin, eyes, and respiratory tract and contact should be avoided.
-Good laboratory practices should be followed during use, and appropriate personal protective equipment should be worn to ensure good ventilation.
-Should be stored in a dry, cool place, away from direct sunlight and high temperature.
-When handling this compound, use appropriate waste disposal methods and comply with local environmental regulations.
Last Update:2024-04-09 02:00:45