4-(Methylsulfonamido)

4-(Methylsulfonamido) - Names and Identifiers

Name	N-(4-aminophenyl)methanesulfonamide
Synonyms	4-(Methylsulfonamido) 4-(Methylsulfonamido)aniline N-(4-AMINOPHENYL)METHANESULFONAMIDE N-(4-Aminophenyl)methanesulfonamide N-(4-aminophenyl)methanesulfonamide Methanesulfonamide, N-(4-aminophenyl)-
CAS	53250-82-1
InChI	InChI=1/C7H10N2O2S/c1-12(10,11)9-7-4-2-6(8)3-5-7/h2-5,9H,8H2,1H3

4-(Methylsulfonamido) - Physico-chemical Properties

Molecular Formula	C7H10N2O2S
Molar Mass	186.23
Density	1.408±0.06 g/cm3(Predicted)
Melting Point	116-117.5 °C
Boling Point	362.2±44.0 °C(Predicted)
Flash Point	172.8°C
Vapor Presure	1.97E-05mmHg at 25°C
pKa	9.90±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.637

4-(Methylsulfonamido) - Introduction

N-(4-aminophenyl)methanesulfonamide is a kind of organic compound, and its chemical formula is C7H10N2O2S. The following is a brief description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline powder
-melting point: 158-160 ℃
-relative molecular mass: 186.24g/mol
-Solubility: Soluble in water and organic solvents such as ethanol and dimethyl sulfoxide

Use:
- N-(4-aminophenyl)methanesulfonamide is an intermediate in organic synthesis, often used in the synthesis of drugs and dyes.
-It can also be used as a substrate in organic synthesis, participating in the amination reaction of carboxylic acids, the sulfonation reaction of amines, etc.

Preparation Method:
N-(4-aminophenyl)methanesulfonamide can be prepared by the following method:
-Reaction of 4-aminoaniline with methanesulfonyl chloride to produce N-(4-aminophenyl) methanesulfonamide.
-The obtained intermediate is further treated under acidic conditions to produce the target product N-(4-aminophenyl)methanesulfonamide.

Safety Information:
- N-(4-aminophenyl)methanesulfonamide has low toxicity, but personal protection is still needed.
-Avoid contact with skin and eyes during operation, and use gloves and goggles for protection.
-In case of contact, rinse immediately with plenty of water and seek medical advice.
-Avoid contact with oxidants and strong acids during storage and handling to avoid dangerous reactions.

Last Update：2024-04-09 02:00:46