N-(4-aminophenyl)methanesulfonamide - Names and Identifiers
N-(4-aminophenyl)methanesulfonamide - Physico-chemical Properties
Molecular Formula | C7H10N2O2S
|
Molar Mass | 186.23 |
Density | 1.408±0.06 g/cm3(Predicted) |
Melting Point | 116-117.5 °C |
Boling Point | 362.2±44.0 °C(Predicted) |
Flash Point | 172.8°C |
Vapor Presure | 1.97E-05mmHg at 25°C |
pKa | 9.90±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.637 |
N-(4-aminophenyl)methanesulfonamide - Introduction
N-(4-aminophenyl)methanesulfonamide is a kind of organic compound, and its chemical formula is C7H10N2O2S. The following is a brief description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder
-melting point: 158-160 ℃
-relative molecular mass: 186.24g/mol
-Solubility: Soluble in water and organic solvents such as ethanol and dimethyl sulfoxide
Use:
- N-(4-aminophenyl)methanesulfonamide is an intermediate in organic synthesis, often used in the synthesis of drugs and dyes.
-It can also be used as a substrate in organic synthesis, participating in the amination reaction of carboxylic acids, the sulfonation reaction of amines, etc.
Preparation Method:
N-(4-aminophenyl)methanesulfonamide can be prepared by the following method:
-Reaction of 4-aminoaniline with methanesulfonyl chloride to produce N-(4-aminophenyl) methanesulfonamide.
-The obtained intermediate is further treated under acidic conditions to produce the target product N-(4-aminophenyl)methanesulfonamide.
Safety Information:
- N-(4-aminophenyl)methanesulfonamide has low toxicity, but personal protection is still needed.
-Avoid contact with skin and eyes during operation, and use gloves and goggles for protection.
-In case of contact, rinse immediately with plenty of water and seek medical advice.
-Avoid contact with oxidants and strong acids during storage and handling to avoid dangerous reactions.
Last Update:2024-04-09 02:00:46