405-04-9
3-Fluoro-4-hydroxybenzonitrile
CAS: 405-04-9
Molecular Formula: C7H4FNO
405-04-9 - Names and Identifiers
405-04-9 - Physico-chemical Properties
| Molecular Formula | C7H4FNO |
| Molar Mass | 137.11 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Melting Point | 133-135°C |
| Boling Point | 253.9±25.0 °C(Predicted) |
| Flash Point | 107.4°C |
| Vapor Presure | 0.0111mmHg at 25°C |
| Appearance | White powder |
| pKa | 6.58±0.18(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.558 |
| MDL | MFCD00215834 |
405-04-9 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | 3439 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
405-04-9 - Reference Information
| use | 3-fluoro-4-hydroxybenzonitrile is an important organic intermediate, mainly used in the preparation of medicines and pesticides, and has a wide range of applications in the manufacturing process of dyes, engineering plastics and photosensitive materials. |
| preparation | traditional methods for synthesizing substituted hydroxybenzonitrile include ammonia oxidation, phase transfer catalytic synthesis or ammonification of benzoic acid. These methods have the disadvantages of long reaction route, large pollution and low yield. For example, 3-fluoro-4-hydroxybenzoic acid is prepared by one-step ammoniation reaction to 3-fluoro-4-hydroxybenzonitrile; 3-fluoro-4-hydroxybenzene is prepared by ammonia oxidation; 3-fluoro-4-hydroxybenzaldehyde is prepared by the reaction of hydroxylamine hydrochloride, and it can also be prepared by 4-hydroxybenzonitrile as the starting material and fluoro reaction [1]. The preparation reaction formula of 3-fluoro-4-hydroxybenzonitrile is as follows: Figure 1 Preparation reaction formula of 3-fluoro-4-hydroxybenzonitrile |
Last Update：2024-04-09 15:16:37
Supplier List
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Request for quotationCAS: 405-04-9
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148
Wechat: 18162425036
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Request for quotationCAS: 405-04-9
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Visit Supplier Webpage Request for quotationCAS: 405-04-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Visit Supplier Webpage Request for quotationCAS: 405-04-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Visit Supplier Webpage Request for quotationCAS: 405-04-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 3-Fluoro-4-hydroxybenzonitrile Visit Supplier Webpage Request for quotation
CAS: 405-04-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 405-04-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Request for quotationCAS: 405-04-9
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148
Wechat: 18162425036
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Request for quotationCAS: 405-04-9
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Visit Supplier Webpage Request for quotationCAS: 405-04-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Visit Supplier Webpage Request for quotationCAS: 405-04-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 3-Fluoro-4-hydroxybenzonitrile Visit Supplier Webpage Request for quotationCAS: 405-04-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 3-Fluoro-4-hydroxybenzonitrile Visit Supplier Webpage Request for quotation
CAS: 405-04-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 405-04-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
405-04-9
(3R,6S)-3,6-dimethyloct-4-yne-3,6-diol
2,4,5-TRIMETHOXYBENZONITRILE
三氟甲基磺酸锂
3,3-二甲基-1-丁基酸酯
2,4-二甲氧基-6-羟基苯甲醛
巴卡亭
109857-81-0
BOC-4-甲氧基-L-苯丙氨酸
替诺福韦酯杂质38
(3R,6S)-3,6-dimethyloct-4-yne-3,6-diol
2,4,5-TRIMETHOXYBENZONITRILE
三氟甲基磺酸锂
3,3-二甲基-1-丁基酸酯
2,4-二甲氧基-6-羟基苯甲醛
巴卡亭
109857-81-0
BOC-4-甲氧基-L-苯丙氨酸
替诺福韦酯杂质38