469-83-0
Cafestol
CAS: 469-83-0
Molecular Formula: C20H28O3
469-83-0 - Names and Identifiers
469-83-0 - Physico-chemical Properties
| Molecular Formula | C20H28O3 |
| Molar Mass | 316.43 |
| Density | 1.23±0.1 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 160-162℃ (Decomposition) (ethyl ether pentane ) |
| Boling Point | 468.6±45.0 °C(Predicted) |
| Specific Rotation(α) | D -101° |
| Solubility | Almost insoluble (0.038g/L) (25°C) |
| Appearance | Powder |
| Color | Off-White to Light Beige |
| pKa | 14.44±0.40(Predicted) |
| Storage Condition | -20°C Freezer, Under inert atmosphere |
| MDL | MFCD01075769 |
469-83-0 - Risk and Safety
| RTECS | PB9185090 |
469-83-0 - Reference
| Reference Show more | 1. Wang Wenqi, Li Yuanyuan, Wang Shuang, Zhu Yanjun, Sun Mengjia, Cai Fujie, Sun Xiaohui, Liu Qing, Zhou Honglei. Study on antiviral active components of total flavonoids from Patrinia villosa L. In vitro [J]. Shandong Science, 2020,33(05):43-50. 2. Dong, Wenjiang, et al. "Comparison of the effect of extraction methods on the quality of green coffee oil from Arabica coffee beans: Lipid yield, fatty acid composition, bioactive components, and antioxidant activity." Ultrasonics Sono chemistry 74 (2021): 3. [IF = 7.491] Wenjiang Dong et al."Comparison of the effect of extraction methods on the quality of green coffee oil from Arabica coffee beans: Lipid yield, fatty acid composition, bioactive components, and antioxidant activity."Ultrason Sonochem. 2021 Jun;74:105578 |
469-83-0 - Reference Information
| biological activity | Cafestol is one of the main components of coffee and a diterpene unique to coffee. Cafestol, an ERK inhibitor against AP-1 targeting activity, inhibits PGE2 production and cyclooxygenase (COX)-2 mRNA expression in LGE-activated RAW264.7 cells. Cafestol strongly inhibit the production of PGE2 by inhibiting NF-kB activation pathway. Cafestol play beneficial effects due to various biological activities, such as chemoprevention, anti-tumor, liver protection, antioxidant and anti-inflammatory effects. |
| target | ERK COX-2 NF-κB |
Last Update：2024-04-09 21:31:58
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Spot supply
Product Name: Cafestol Visit Supplier Webpage Request for quotationCAS: 469-83-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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