482646-13-9 - Names and Identifiers
482646-13-9 - Physico-chemical Properties
| Molecular Formula | C18H18N4O2S
|
| Molar Mass | 354.43 |
| Storage Condition | -20°C，干燥，密封 |
| In vitro study | A2ti-2 (compound 7a) is an annexin A2-S100A10 protein-protein interaction blocker. A2ti-2 is less effective with <50% reduction in HPV16 PsV infection achieved at 100 μM. A2ti-1 decreases HPV16 entry with a 20% reduction at 100 μM. |
482646-13-9 - Reference Information
| Biological activity | A2ti-2 is selective, low affinity annexin A2/S100A10 isotetramer (A2t) inhibitor, IC50 is 230 μM. A2ti-2 specifically disrupt the protein interaction between A2 and S100A10. A2ti-2 can prevent human papillomavirus type 16 (HPV16) infection. |
| target | IC50: 230 μM (A2t) |
| in vitro study | A2ti-2 (compound 7a) is an annexin A2-S100A10 protein-protein interaction blocker. A2ti-2 is less effective with <50% reduction in HPV16 PsV infection achieved at 100 μ m. A2ti-1 decreases HPV16 entry with a 20% reduction at 100 μ m. |
Last Update：2024-04-10 22:29:15
