4H-1,2,4-Triazole,4-(4-hydrazinylphenyl)-

4H-1,2,4-Triazole,4-(4-hydrazinylphenyl)- - Names and Identifiers

Name	4H-1,2,4-Triazole,4-(4-hydrazinophenyl)-(9CI)
Synonyms	4-(4-Hydrazinophenyl)-4H-1,2,4-triazole 4-(4-hydrazinophenyl)-4H-1,2,4-triazole 1-(4-hydrazinylphenyl)-1H-1,2,4-triazole 4-(4-hydrazinylphenyl)-4H-1,2,4-triazole 4H-1,2,4-Triazole,4-(4-hydrazinylphenyl)- 4H-1,2,4-Triazole, 4-(4-hydrazinophenyl)- 4H-1,2,4-Triazole,4-(4-hydrazinophenyl)-(9CI) 4-(4-HYDRAZINOPHENYL)-1,2,4-TRIAZOLEHYDROCHLORIDE
CAS	154594-16-8
InChI	InChI=1/C8H9N5/c9-12-7-1-3-8(4-2-7)13-5-10-11-6-13/h1-6,12H,9H2

4H-1,2,4-Triazole,4-(4-hydrazinylphenyl)- - Physico-chemical Properties

Molecular Formula	C8H9N5
Molar Mass	175.19
Density	1.39±0.1 g/cm3(Predicted)
Boling Point	410.1±47.0 °C(Predicted)
Flash Point	201.8°C
Vapor Presure	6.16E-07mmHg at 25°C
pKa	4.88±0.30(Predicted)
Storage Condition	2-8°C
Refractive Index	1.712

4H-1,2,4-Triazole,4-(4-hydrazinylphenyl)- - Introduction

4-(4-hydrazinophenyl)-1,2, 4-triazole hydrochloride, also known as hydrazinotriazole hydrochloride, its properties, uses, preparation and safety information are as follows:

Nature:
-Appearance: A colorless to light yellow crystalline solid.
-Solubility: Soluble in water and some organic solvents.
-Stability: relatively stable at room temperature and can be stored for a long time under dry conditions.

Use:
-Pharmaceutical field: Hydrazinotriazole hydrochloride is an important drug intermediate, which can be used to synthesize or prepare a variety of drugs, such as anti-cancer drugs.
-Pesticide field: Hydrazinotriazole hydrochloride can also be used as an intermediate for fungicides and plant growth regulators.

Method:
Hydrazinotriazole hydrochloride is typically synthesized by the following steps:
1. In glacial acetic acid to add hydrogen to sodium metal, and hydrazine reaction to form the sodium salt of hydrazine.
2. The sodium salt of hydrazine is reacted with 4-tert-butylbenzoyl chloride to generate 4-(4-hydrazinophenyl)-1,2, 4-triazole.
3. Finally, 4-(4-hydrazinophenyl)-1,2, 4-triazole was reacted with hydrochloric acid to obtain hydrazinotriazole hydrochloride.

Safety Information:
-Hydrazinotriazole hydrochloride has certain toxicity and irritation, should avoid inhalation, contact with skin and ingestion.
-Use should wear appropriate protective clothing and gloves to ensure a well-ventilated working environment.
-Avoid dust or splashing solution during operation to avoid respiratory tract, eye and skin irritation.
-In case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.

Please note that this information is for reference only and that the safety data sheets and operating procedures for the relevant chemicals are also required for specific use.

Last Update：2024-04-09 21:00:56