5,6,7,8-tetrahydroisoquinoline

5,6,7,8-tetrahydroisoquinoline - Names and Identifiers

Name	5,6,7,8-tetrahydroisoquinoline
Synonyms	3,4-CYCLOHEXENOPYRIDINE 5,6,7,8-Tetrahydroisoquinoline 5,6,7,8-tetrahydroisoquinoline 5,6,7,8-TETRAHYDROISOQUINOLINE Isoquinoline,5,6,7,8-tetrahydro- 4-(1-pyrrolidinyl)-1-(3-thiophenyl)-1-butanol hydrochloride
CAS	36556-06-6
EINECS	253-098-4
InChI	InChI=1/C9H11N/c1-2-4-9-7-10-6-5-8(9)3-1/h5-7H,1-4H2
InChIKey	HTMGQIXFZMZZKD-UHFFFAOYSA-N

5,6,7,8-tetrahydroisoquinoline - Physico-chemical Properties

Molecular Formula	C9H11N
Molar Mass	133.19
Density	1.03g/mLat 25°C(lit.)
Melting Point	146.5°C
Boling Point	106-108°C13mm Hg(lit.)
Flash Point	212°F
Vapor Presure	0.172mmHg at 25°C
Appearance	Liquid
Color	Clear pale yellow
pKa	6.37±0.20(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	n20/D 1.545(lit.)
MDL	MFCD00012168

5,6,7,8-tetrahydroisoquinoline - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
HS Code	29334900

5,6,7,8-tetrahydroisoquinoline - Introduction

5,6,7,8-tetrahydroisoquinoline is an organic compound with the chemical formula C9H11NO4. The following is its nature, use, preparation and safety information:

Nature:
1. Appearance: 5,6,7,8-tetrahydroisoquinoline is a white solid.
2. melting point: its melting point is between 155-160 ℃.
3. Solubility: The compound is soluble in organic solvents such as water, alcohol and chloroform.

Use:
5,6,7,8-tetrahydroisoquinoline, as an organic synthesis intermediate, has a wide range of applications:
1. Drug research: It can be used to synthesize certain drugs, such as anti-cancer drugs, antidepressants, etc., so it has important research value in the field of medicine.
2. photosensitive material: it can be used for the synthesis of photosensitive materials, such as photosensitizers, photopolymers and photovoltaic cells.

Preparation Method:
the preparation method of 5,6,7,8-tetrahydroisoquinoline can be briefly introduced as follows:
1. First, through a suitable synthesis method, a suitable compound (such as a compound with a-NO2 functional group on the benzene ring) is reacted with aminoethanol to generate the corresponding amide compound.
2. Then, the amide compound is converted into 5,6,7,8-tetrahydroisoquinoline by a corresponding reaction such as reduction or oxidation.

Safety Information:
Regarding the safety of 5,6,7,8-tetrahydroisoquinoline, the following points need to be noted:
1. The compound is an unstable compound at room temperature and may react spontaneously, causing fire or explosion.
2. When using or handling the compound, wear appropriate personal protective equipment, including chemical protective glasses, gloves and protective clothing.
3. avoid inhalation or contact with the compound, should maintain good ventilation conditions.
4. When handling the compound, do not directly discharge it into the environment, and treat and dispose of waste in strict accordance with relevant regulations.

In the laboratory or production process, the necessary safety measures should be carefully evaluated and taken according to the specific situation. It is also recommended that the relevant safety guidelines and procedures be consulted and observed before using the compound.

Last Update：2024-04-09 21:01:54