5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde
5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde
CAS: 128455-62-9
Molecular Formula: C6H4ClF3N2O
5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde - Names and Identifiers
5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde - Physico-chemical Properties
| Molecular Formula | C6H4ClF3N2O |
| Molar Mass | 212.56 |
| Density | 1.56±0.1 g/cm3(Predicted) |
| Melting Point | 42-44°C |
| Boling Point | 239.6±40.0 °C(Predicted) |
| Flash Point | 98.7°C |
| Vapor Presure | 0.0396mmHg at 25°C |
| pKa | -4.03±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.501 |
5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde - Introduction
5-Chloro-1-methyl-3-(trifluoromethyl) pyrazole-4-carbaldehyde is an organic compound with the formula C7H4ClF3N2O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow solid.
-Melting point: approximately 92-100°C.
-Boiling point: about 280-281°C.
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide.
-Stability: relatively stable under normal storage and operating conditions.
Use:
-It is an important organic synthesis intermediate that can be used to synthesize other organic compounds.
-Because it has chlorine, methyl and trifluoromethyl groups, it is often used as a starting material for the synthesis of drugs and pesticides in the field of medicinal chemistry and pesticide chemistry.
-It can also be used in the synthesis of dyes, paints and other organic materials.
Preparation Method:
The preparation method of 5-chloro-1-methyl-3-(trifluoromethyl) pyrazole-4-carbaldehyde can be carried out by the following steps:
1.3-bromo -5-chloropyrazole and trifluoromethyl chloride are first reacted to give 3-(trifluoromethyl)-5-chloropyrazole.
2.3-(trifluoromethyl)-5-chloropyrazole reacts with formaldehyde under alkaline conditions to give 5-chloro -1-methyl -3-(trifluoromethyl) pyrazole -4-carbaldehyde.
Safety Information:
- 5-Chloro -1-methyl -3-(trifluoromethyl) pyrazole-4-formaldehyde should be operated in a well-ventilated place to avoid inhaling its steam or dust.
-Wear appropriate protective gloves, glasses and protective clothing when using.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water. If discomfort occurs, seek medical treatment.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
Nature:
-Appearance: Colorless to light yellow solid.
-Melting point: approximately 92-100°C.
-Boiling point: about 280-281°C.
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide.
-Stability: relatively stable under normal storage and operating conditions.
Use:
-It is an important organic synthesis intermediate that can be used to synthesize other organic compounds.
-Because it has chlorine, methyl and trifluoromethyl groups, it is often used as a starting material for the synthesis of drugs and pesticides in the field of medicinal chemistry and pesticide chemistry.
-It can also be used in the synthesis of dyes, paints and other organic materials.
Preparation Method:
The preparation method of 5-chloro-1-methyl-3-(trifluoromethyl) pyrazole-4-carbaldehyde can be carried out by the following steps:
1.3-bromo -5-chloropyrazole and trifluoromethyl chloride are first reacted to give 3-(trifluoromethyl)-5-chloropyrazole.
2.3-(trifluoromethyl)-5-chloropyrazole reacts with formaldehyde under alkaline conditions to give 5-chloro -1-methyl -3-(trifluoromethyl) pyrazole -4-carbaldehyde.
Safety Information:
- 5-Chloro -1-methyl -3-(trifluoromethyl) pyrazole-4-formaldehyde should be operated in a well-ventilated place to avoid inhaling its steam or dust.
-Wear appropriate protective gloves, glasses and protective clothing when using.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water. If discomfort occurs, seek medical treatment.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-09 02:00:41
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Product Name: 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXALDEHYDE Visit Supplier Webpage Request for quotation
CAS: 128455-62-9
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CAS: 128455-62-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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