5-Methoxy-1H-benzoiMidazole - Names and Identifiers
5-Methoxy-1H-benzoiMidazole - Physico-chemical Properties
Molecular Formula | C8H8N2O
|
Molar Mass | 148.16 |
Density | 1.244±0.06 g/cm3(Predicted) |
Melting Point | 121-126 °C (lit.) |
Boling Point | 190-195 °C(Press: 0.03 Torr) |
Flash Point | 141.7°C |
Vapor Presure | 6.07E-06mmHg at 25°C |
pKa | 13.12±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.647 |
MDL | MFCD00272526 |
5-Methoxy-1H-benzoiMidazole - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
HS Code | 29332990 |
5-Methoxy-1H-benzoiMidazole - Introduction
5-Methoxybenzimidazole(5-Methoxybenzimidazole) is an organic compound with the chemical formula C8H8N2O. It is a white crystalline solid, stable at room temperature.
Nature:
1. melting point: 136-138 ℃.
2. Insoluble in water at room temperature, slightly soluble in hot and cold benzene, dichloromethane and ether solvents.
3. It is a weak base, soluble in acidic solution.
Use:
1.5-Methoxybenzimidazole can be used as a synthetic starting material for antifungal and antiviral drugs.
2. It can also be used to synthesize biologically active compounds, such as fungicides, drug intermediates, etc.
Preparation Method:
A common preparation method is to react benzimidazole with methanesulfonic acid to generate 5-methylbenzimidazole, and then perform a methyl etherification reaction to obtain 5-Methoxybenzimidazole.
Safety Information:
1. 5-Methoxybenzimidazole has a stimulating effect on the skin and eyes, and should be rinsed with plenty of water immediately after contact.
2. during use and storage, avoid contact with heat sources and open flames.
3. in the process of operation should pay attention to personal protection, wear protective gloves and goggles. In case of accidental ingestion or inhalation, seek medical attention immediately.
Last Update:2024-04-09 02:00:46