5-Methoxy-2-(trifluoromethyl)pyridine

5-Methoxy-2-(trifluoromethyl)pyridine - Names and Identifiers

Name	5-Methoxy-2-(trifluoromethyl)pyridine
Synonyms	NCR CF E1 NCR CF E1 [WLN] 5-Methoxy-2-(trifluoromethyl)p 5-Methoxy-2-(trifluoromethyl)pyridine Pyridine, 5-methoxy-2-(trifluoromethyl)- 5-Methoxy-alpha,alpha,alpha-trifluoro-2-picoline
CAS	216766-13-1
EINECS	1308068-626-2
InChI	InChI=1/C8H6FN/c1-6-2-7(5-10)4-8(9)3-6/h2-4H,1H3

5-Methoxy-2-(trifluoromethyl)pyridine - Physico-chemical Properties

Molecular Formula	C7H6F3NO
Molar Mass	177.12
Density	1.263±0.06 g/cm3(Predicted)
Boling Point	176.8±40.0 °C(Predicted)
Flash Point	88.7°C
Vapor Presure	0.171mmHg at 25°C
pKa	-1.48±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.507

5-Methoxy-2-(trifluoromethyl)pyridine - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Hazard Class	IRRITANT

5-Methoxy-2-(trifluoromethyl)pyridine - Introduction

5-Methoxy-2-(trifluoromethyl)pyridine is an organic compound. The following is its nature, use, preparation and safety information:

Nature:
-chemical formula: C8H6F3NO
-Molecular Weight: 189.13
-Appearance: Light yellow liquid
-Melting point:-14 ° C
-Boiling point: 134-136 ° C
-Density: 1.35g/cm³

Use:
- 5-Methoxy-2-(trifluoromethyl)pyridine is a commonly used reagent in organic synthesis, which can be used to synthesize other organic compounds, such as pharmaceutical intermediates and pesticides.
-It is also used as a solvent in organic synthesis.

Method:
-5-methoxy -2-(trifluoromethyl)pyridine can be obtained by reacting methoxypyridine with a trifluoromethyl compound.
-A specific synthesis method may be, under an inert atmosphere, reacting methoxypyridine with trifluoromethanesulfonic acid or trifluoroacetic acid.

Safety Information:
- 5-Methoxy-2-(trifluoromethyl)pyridine is an organic compound that should be handled with caution to avoid contact with skin, eyes or inhalation.
-During use and storage, Good Laboratory safety practices need to be observed.
-When handling this compound, take appropriate personal protective measures, such as wearing protective glasses, gloves and laboratory coats.
-In addition, 5-Methoxy-2-(trifluoromethyl)pyridine should be stored in a sealed container, away from heat and fire sources.

Please follow the correct safety operation guidelines when operating and using 5-Methoxy-2-(trifluoromethyl)pyridine, and consult relevant professionals according to the situation.

Last Update：2024-04-09 02:00:44