5-bromo-2-methoxy-pyridine-3-carbaldehyde - Names and Identifiers
5-bromo-2-methoxy-pyridine-3-carbaldehyde - Physico-chemical Properties
Molecular Formula | C7H6BrNO2
|
Molar Mass | 216.03 |
Density | 1.606±0.06 g/cm3(Predicted) |
Melting Point | 93-100 °C |
Boling Point | 278.5±35.0 °C(Predicted) |
Flash Point | 122.2°C |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0.00424mmHg at 25°C |
Appearance | White to brown solid or powder or crystal |
Color | White to brown |
pKa | -0.76±0.20(Predicted) |
Storage Condition | 2-8°C |
Sensitive | Air Sensitive |
Refractive Index | 1.591 |
MDL | MFCD05663521 |
Physical and Chemical Properties | Sensitivity: Air Sensitive |
5-bromo-2-methoxy-pyridine-3-carbaldehyde - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
WGK Germany | 3 |
HS Code | 29333990 |
Hazard Class | IRRITANT |
5-bromo-2-methoxy-pyridine-3-carbaldehyde - Introduction
5-Bromo-2-methoxypyridine-3-carbaldehyde, chemical formula C8H8BrNO2, molecular weight 216.06g/mol. The following is a description of its nature, use, preparation and safety information:
Nature:
5-Bromo-2-methoxypyridine-3-carbaldehyde is a yellow solid with a special fragrance. It has a strong pungent odor and is volatile. It dissolves easily in solvents and melts below 340 degrees Celsius. In addition, it is also a compound with bacteriostatic activity.
Use:
5-bromo-2-methoxypyridine-3-carbaldehyde is commonly used in the field of organic synthesis. It can be used as aldehyde reagent, aromatic aldehyde and amine exchange reaction reagent, photosensitive dyes, intermediates in organic synthesis. It is also used as a potential drug molecule in pharmaceutical research.
Preparation Method:
The synthesis method of 5-bromo-2-methoxypyridine-3-carbaldehyde is generally obtained by a reaction on a pyridine ring. 2-Bromo-5-methoxypyridine can be prepared first, followed by a base-catalyzed alcoholic hydroxyl substitution reaction with methanol to form the desired product.
Safety Information:
5-bromo -2-methoxypyridine -3-formaldehyde needs to pay attention to safety during use. It is irritating and volatile and may cause irritation of the eyes, skin and respiratory tract. Therefore, protective glasses, gloves and protective masks should be worn during operation. At the same time, it is also a potential carcinogen, and appropriate ventilation measures and protective measures should be taken to avoid inhalation. During storage, it should be kept in a dry and cool place, separated from oxidants, acids and other substances to avoid contact with fire sources. In case of any discomfort or accident, stop using it immediately and consult the relevant safety operation guide.
Last Update:2024-04-09 21:11:58