5-ethyl-2-thiouracil
5-ethyl-2-thiouracil
CAS: 34171-37-4
Molecular Formula: C6H8N2OS
5-ethyl-2-thiouracil - Names and Identifiers
5-ethyl-2-thiouracil - Physico-chemical Properties
| Molecular Formula | C6H8N2OS |
| Molar Mass | 156.21 |
| Melting Point | 191-193℃ |
| Solubility | DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | Pale Yellow to Pale Beige |
| Storage Condition | 2-8°C |
5-ethyl-2-thiouracil - Risk and Safety
| WGK Germany | 3 |
| HS Code | 29335990 |
5-ethyl-2-thiouracil - Introduction
5-ethyl-2-thiouracil(5-ethyl-2-thiouracil) is an organic compound with the chemical formula C7H10N2OS. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-ethyl-2-thiouracil is white crystal or crystalline powder.
-Solubility: It is slightly soluble in water, soluble in alcohol, methanol and ethanol.
-Melting point: Its melting point is about 206~209 degrees Celsius.
Use:
-Medical field: 5-ethyl-2-thiouracil is widely used as an intermediate for the synthesis of biologically active substances. It has an anti-hyperthyroidism effect and can treat hyperthyroidism.
-Cosmetics field: It is also used in some cosmetics and has the effect of regulating skin pigmentation.
Preparation Method:
The preparation of 5-ethyl-2-thiouracil is usually carried out by the following steps:
1. First, acetylacetone (Acetylated acetone) is reacted with thiouracil (Thiouracil) to obtain acetylbutanedione thiouracil (Acetylated).
2. Then, base-catalyzed acylation of ethylacetone thiouracil was carried out to obtain 5-ethyl-2-thiouracil.
Safety Information:
- 5-ethyl-2-thiouracil should be used and handled in accordance with safe operating procedures.
-It may cause irritation to the eyes, skin and respiratory system, so be careful to avoid contact when using it.
-Wear appropriate protective equipment such as chemical glasses and gloves during operation.
-During storage and transportation, it should be kept in a sealed container, away from fire and oxidizing agents.
-Observe local regulations when disposing of waste and avoid releasing it into the environment.
Nature:
-Appearance: 5-ethyl-2-thiouracil is white crystal or crystalline powder.
-Solubility: It is slightly soluble in water, soluble in alcohol, methanol and ethanol.
-Melting point: Its melting point is about 206~209 degrees Celsius.
Use:
-Medical field: 5-ethyl-2-thiouracil is widely used as an intermediate for the synthesis of biologically active substances. It has an anti-hyperthyroidism effect and can treat hyperthyroidism.
-Cosmetics field: It is also used in some cosmetics and has the effect of regulating skin pigmentation.
Preparation Method:
The preparation of 5-ethyl-2-thiouracil is usually carried out by the following steps:
1. First, acetylacetone (Acetylated acetone) is reacted with thiouracil (Thiouracil) to obtain acetylbutanedione thiouracil (Acetylated).
2. Then, base-catalyzed acylation of ethylacetone thiouracil was carried out to obtain 5-ethyl-2-thiouracil.
Safety Information:
- 5-ethyl-2-thiouracil should be used and handled in accordance with safe operating procedures.
-It may cause irritation to the eyes, skin and respiratory system, so be careful to avoid contact when using it.
-Wear appropriate protective equipment such as chemical glasses and gloves during operation.
-During storage and transportation, it should be kept in a sealed container, away from fire and oxidizing agents.
-Observe local regulations when disposing of waste and avoid releasing it into the environment.
Last Update：2024-04-09 21:01:54
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