5-氯-4-苯基噻唑 - Names and Identifiers
5-氯-4-苯基噻唑 - Physico-chemical Properties
| Molecular Formula | C9H6ClNS
|
| Molar Mass | 195.67 |
| Storage Condition | 2-8°C |
5-氯-4-苯基噻唑 - Upstream Downstream Industry
5-氯-4-苯基噻唑 - Introduction
5-choro-4-phenylthiazole is an organic compound with the chemical formula C10H6ClNS. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 5-chroo-4-phenylthiazole is a white crystalline solid.
-Solubility: It has good solubility in most organic solvents.
-Melting point: Its melting point is about 109-110 degrees Celsius.
Use:
-Chemical reactant: 5-chroo-4-phenylthiazole can be used as a reactant in organic synthesis and used to synthesize other organic compounds, such as drugs and dyes.
-Pesticide intermediate: It can also be used as an intermediate for pesticides and used to synthesize pesticide varieties.
Method:
-5-choro-4-phenylthiazole can be synthesized by the following steps:
1. Under alkaline conditions, acetophenone and tert-butyl sulfoyl oxalate react to generate 5-acetyl Benzo is ketone.
2. Use thioester imine reagent to react 5-acetyl Benzo is ketone and phosphorus pentachloride to generate 5-chloro -4-acetyl benzothiazole.
3. Further react 5-chloro -4-acetyl benzothiazole with acetic acid and iodine to obtain the final product 5-Chloro-4-phenylthiazole.
Safety Information:
-5-choro-4-phenylthiazole has no obvious danger under normal conditions of use.
-However, as a general safety measure for handling chemicals, it is recommended to wear appropriate protective gloves and goggles.
-It should also be used in a well-ventilated place to avoid inhalation or skin contact. In case of accidental inhalation or contact, seek medical attention immediately.
-When storing, it should be kept in a dark, dry and well-ventilated place, away from fire and flammable substances.
Please note that when using chemicals, always follow correct operating procedures and strictly follow safety precautions.
Last Update：2024-04-09 15:18:03