52578-60-6
1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one
CAS: 52578-60-6
Molecular Formula: C8H6BrNO
52578-60-6 - Names and Identifiers
52578-60-6 - Physico-chemical Properties
| Molecular Formula | C8H6BrNO |
| Molar Mass | 212.04 |
| Boling Point |
52578-60-6 - Introduction
1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one is an organic compound with the formula C16H19BrN2O3. The following is its nature, use, preparation and safety information:
Nature:
1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one exists as a solid with the appearance of white crystals or crystalline powder. It has a high melting point, is soluble in some common organic solvents such as dimethylformamide (DMF) and dichloromethane, and is insoluble in water.
Use:
1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one is an important intermediate compound, which is widely used in the preparation of various drugs, natural products and pesticides in organic synthesis. It can be used for the synthesis of indole derivatives, indole alkaloids, indole anti-tumor drugs.
Preparation Method:
1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one can be prepared by a variety of synthetic methods. One commonly used method of preparation is the reaction of 1-tert-butoxycarbonyl-6-chloro-1, 2-dihydro-3H-indol-3-one with potassium bromide under alkaline conditions. For specific synthetic steps, please check the organic synthesis literature.
Safety Information:
When handling 1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one, appropriate safety measures need to be taken. It is an organic compound with certain toxicity and irritation. Wear appropriate personal protective equipment to avoid contact with skin and eyes. At the same time, operate in a well-ventilated place to avoid inhaling its steam or dust. If exposed or inhaled, seek medical attention immediately.
Please note that the use and handling of chemicals in the chemical laboratory requires strict compliance with safe operating procedures, and refer to the safety data sheet provided by the manufacturer and the laboratory's safe operating instructions.
Nature:
1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one exists as a solid with the appearance of white crystals or crystalline powder. It has a high melting point, is soluble in some common organic solvents such as dimethylformamide (DMF) and dichloromethane, and is insoluble in water.
Use:
1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one is an important intermediate compound, which is widely used in the preparation of various drugs, natural products and pesticides in organic synthesis. It can be used for the synthesis of indole derivatives, indole alkaloids, indole anti-tumor drugs.
Preparation Method:
1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one can be prepared by a variety of synthetic methods. One commonly used method of preparation is the reaction of 1-tert-butoxycarbonyl-6-chloro-1, 2-dihydro-3H-indol-3-one with potassium bromide under alkaline conditions. For specific synthetic steps, please check the organic synthesis literature.
Safety Information:
When handling 1-Boc-6-broMo-1,2-dihydro-3H-indol-3-one, appropriate safety measures need to be taken. It is an organic compound with certain toxicity and irritation. Wear appropriate personal protective equipment to avoid contact with skin and eyes. At the same time, operate in a well-ventilated place to avoid inhaling its steam or dust. If exposed or inhaled, seek medical attention immediately.
Please note that the use and handling of chemicals in the chemical laboratory requires strict compliance with safe operating procedures, and refer to the safety data sheet provided by the manufacturer and the laboratory's safe operating instructions.
Last Update：2024-04-09 21:11:58
