| Name | Glycinamide |
| Synonyms | Glycinamide AMINOACETAMIDE 2-amino-acetamid 2-Aminoacetamide 2-azanylethanamide Acetamide, 2-amino- Aminoacetimidic acid 2-Amino-1-iminoethanol |
| CAS | 598-41-4 |
| EINECS | 209-932-4 |
| Molecular Formula | C2H6N2O |
| Molar Mass | 74.08 |
| Density | 1.122±0.06 g/cm3(Predicted) |
| Melting Point | 65-67 °C |
| Boling Point | 281.3±23.0 °C(Predicted) |
| Physical and Chemical Properties | Chemical properties needle-like crystals. Melting point 67-68 ℃. Soluble in water, ethanol and methanol, soluble in acetone, chloroform and ethyl acetate, slightly soluble in ether and benzene. It is a strong alkaline reaction and can absorb carbon dioxide. It reacts with hot water to produce glycine and ammonia. |
| Use | Uses organic synthetic intermediates, feed additives, food additives and raw materials of α-amino acids. |
| Downstream Products | 2-Benzylidenemalonaldehyde Z-GLY-NH2 DL-Serine |
| storage conditions | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| acidity coefficient (pKa) | pK1: 7.95( 1) (25°C) |
| NIST chemical information | H2NCH2CONH2 (glycinamide)(598-41-4) |
| EPA chemical information | Acetamide, 2-amino- (598-41-4) |
(1) in the presence of strong alkaline substances and ketone compounds, water is added to a water-soluble solvent to decompose amino acetonitrile. 11.2g of 50% amino acetonitrile aqueous solution, 5.8g of acetone and 0.5ml of NaOH equivalent solution are added into a 50ml three-mouth bottle equipped with a stirrer and a thermometer. after stirring at 20 ℃ for 1h, the pH value of the reaction solution slowly decreases from the 15.1 at the beginning, the reaction is completed and the yield is 100%. (2) By the action of chloroacetamide and ammonia water, the chloroacetamide and concentrated ammonia water are stirred and reacted below 10 ℃ for 2 hours, then heated to 25 ℃, stirred and reacted with ammonia until the white crystals of chloroacetamide disappear, and then concentrated under reduced pressure at 50-60 ℃ until crystallization begins to be precipitated.