6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Names and Identifiers

Name	6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one
Synonyms	ERLOTINIBINT-F Erlotinib iMpurity E Erlotinib'S Intermediate Erlotinib LactaM IMpurity 6,7-bis-Methoxyethoxy-quinazolin-4-one 6,7-Bis(2-Methoxyethoxy)Quinazolin-4(1H)-One 6,7-Bis(2-Methoxyethoxy)-3H-quinazolin-4-one 6,7-bis(2-methoxyethoxy)-1H-quinazolin-4-one 6,7-BIS(2-METHOXYETHOXY)QUINAZOLIN-4(1H)-ONE 6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one 6,7-Bis-(2-Methoxyethoxy)Quinazolin-4(3H)-One 6,7-Bis-(2-Methoxyethoxy)-4(3H)-Quinazolinone 6,7-Bis-(2-Methoxyethoxy)-Quinazolin-4(3H)-One 6,7-Bis(2-Methoxyethoxy)-3,4-Dihydroquinazolin-4-One Methyl Ester, 2-Amino-4,5-Bis(2-Methoxyethoxy)Benzoic Acid 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone 6,7-BIS(2-METHOXYETHOXY)QUINAZOLIN-4(1H)-ONE
CAS	179688-29-0
EINECS	605-867-4
InChI	InChI=1/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
InChIKey	PMQWTUWLIGJTQD-UHFFFAOYSA-N

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Physico-chemical Properties

Molecular Formula	C14H18N2O5
Molar Mass	294.3
Density	1.26±0.1 g/cm3(Predicted)
Melting Point	185-189°C
Boling Point	467.8±55.0 °C(Predicted)
Flash Point	236.7°C
Solubility	DMSO: ≥10mg/mL
Vapor Presure	6.3E-09mmHg at 25°C
Appearance	White crystal
Color	off-white to light tan
pKa	1.35±0.20(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.552
MDL	MFCD02678087

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Risk and Safety

WGK Germany

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Introduction

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

Last Update：2022-10-16 17:14:31

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Reference Information

Introduction

6, 7-dimethoxyquinazolin-4-one is an intermediate for the synthesis of erlotinib. Erlotinib, chemical name N-(3-acetylenephenyl)-6, 7-bis (2-methoxyethoxy)-4-quinolinamide, is a small molecule compound that can inhibit human epidermal growth factor receptor (EGFR) Signaling pathway, erlotinib inhibits tumor growth by inhibiting the activity of tyrosine kinase.

Last Update：2024-04-09 20:44:15

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one

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View History

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one
3-Piperidinylmethyl 4-methoxybenzoatehydrochloride
Hexanoic acid, 6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
6-马来酰亚胺基己酸 N-琥珀酰亚胺酯
二乙三胺五乙酸铁氢钠盐
(1R,2S,5S)-2-氨基-5-(二甲基氨基羰基)环己基氨基甲酸叔丁酯草酸盐依度沙班中间体
磷酸-4-硝基苯酯二钠盐
5-Bromo-2-Hydroxy-3-Nitroacetophenone
4-羟甲基立方烷羧酸甲酯
1-乙酰基-3-吡咯烷甲酸

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one

CAS: 179688-29-0

Molecular Formula: C14H18N2O5

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Names and Identifiers

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Physico-chemical Properties

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Risk and Safety

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Introduction

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Reference Information

Supplier List

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one Request for Quotation

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one

CAS: 179688-29-0

Molecular Formula: C14H18N2O5

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Names and Identifiers

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Physico-chemical Properties

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Risk and Safety

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Introduction

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one - Reference Information

Supplier List

6,7-Bis(2-methoxyethoxy)quinazolin-4-(3H)-one