6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
GAK inhibitor 49
CAS: 319492-82-5
Molecular Formula: C20H22N2O5
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine - Names and Identifiers
| Name | GAK inhibitor 49 |
| Synonyms | GAK inhibitor 49 6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine 4-Quinolinamine, 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)- |
| CAS | 319492-82-5 |
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine - Physico-chemical Properties
| Molecular Formula | C20H22N2O5 |
| Molar Mass | 370.4 |
| Density | 1.223±0.06 g/cm3(Predicted) |
| Boling Point | 494.8±45.0 °C(Predicted) |
| pKa | 7?+-.0.50(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | GAK inhibitor 49 (compound 49) shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC 50 s of 28, 63 and >100 μM, respectively. |
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 0 ml | 0 ml | 0 ml |
| 5 mM | 0 ml | 0 ml | 0 ml |
| 10 mM | 0 ml | 0 ml | 0 ml |
| 5 mM | 0 ml | 0 ml | 0 ml |
Last Update：2024-01-02 23:10:35
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine - Reference Information
| biological activity | GAK inhibitor 49 is an ATP-competitive, highly selective cyclin G-related kinase (GAK) inhibitors, Ki is 0.54 nM, cell IC50 is 56 nM. GAK inhibitor 49 was also shown to bind to ripk2. |
Last Update：2024-04-09 22:09:11
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tech@medchemexpress.com
Mobile: 609-228-6898
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Product Name: GAKinhibitor49 Visit Supplier Webpage Request for quotationCAS: 319492-82-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
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View History
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
反式-四氢呋喃-3,4-二羧酸
TIMTEC-BB SBB003650
1,4-二氨基-2,3-二氰基蒽醌
bis(chloromethyl)
Tin(II) ethoxide
乙二胺四乙酸三钠
2-Chloro-8-Methoxyquinazolin-4-aMine
Apple zinc
三氟乙酸铜水合物
反式-四氢呋喃-3,4-二羧酸
TIMTEC-BB SBB003650
1,4-二氨基-2,3-二氰基蒽醌
bis(chloromethyl)
Tin(II) ethoxide
乙二胺四乙酸三钠
2-Chloro-8-Methoxyquinazolin-4-aMine
Apple zinc
三氟乙酸铜水合物