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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameGAK inhibitor 49
SynonymsGAK inhibitor 49;6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine;4-Quinolinamine, 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)-
CAS319492-82-5
EINECS
Chemical FormulaC20H22N2O5
Molecular Weight370.4
inchi
Package1 mg;5 mg;10 mg;25 mg;50 mg
PriceEmail to quote
DescriptionsGAK inhibitor 49

GAK inhibitor 49

MedChemExpress (MCE)

HY-124793

319492-82-5

98.79%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

GAK inhibitor 49

GAK inhibitor 49

MedChemExpress (MCE)

HY-124793

319492-82-5

98.79%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

GAK inhibitor 49 is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 also shows binding to RIPK2.

GAK inhibitor 49 (compound 49) shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC50s of 28, 63 and >100 μM, respectively[1].

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[1]. Asquith CRM, et al. Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem. 2018
13(1):48-66. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/gak-inhibitor-49.html
Last Update2025-05-21 16:50:25
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