6-AMINOCHRYSENE
6-Aminochrysene
CAS: 2642-98-0
Molecular Formula: C18H13N
6-AMINOCHRYSENE - Names and Identifiers
| Name | 6-Aminochrysene |
| Synonyms | ADCA 6-Amc Chrysenex Chrysonex AMINOCHRYSENE 6-CHRYSENAMINE 6-Chrysenamine 6-Aminochrysene 6-AMINOCHRYSENE chrysen-6-amine chrysen-6-ylamine AMINOCHRYSENE, 6- |
| CAS | 2642-98-0 |
| EINECS | 220-149-7 |
| InChI | InChI=1/C18H13N/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H,19H2 |
6-AMINOCHRYSENE - Physico-chemical Properties
| Molecular Formula | C18H13N |
| Molar Mass | 243.3 |
| Density | 0.8933 (rough estimate) |
| Melting Point | 209-211°C(lit.) |
| Boling Point | 376.18°C (rough estimate) |
| Flash Point | 286.9°C |
| Water Solubility | 155ug/L(24 ºC) |
| Solubility | Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly, Heated) |
| Vapor Presure | 3.56E-10mmHg at 25°C |
| Appearance | Solid |
| Color | Yellow to Brown |
| Merck | 13,2275 |
| pKa | 4.32±0.30(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4500 (estimate) |
| In vitro study | 6-Aminochrysene inhibits the hydroxylation of aniline, 0-demethylation of p-nitroanisole, and N-demethylation of aminopyrine by rat liver microsomes. Pre-treatment of rats with 6-aminochrysene markedly decreases the N-demethylation in vitro but significantly increases the hydroxylation and the 0-demethylation. |
| In vivo study | 6-Aminochrysene is an inhibitor of the growth of several solid experimental tumours in vivo and has a cancerostatic effect on human breast cancer. Long term topical skin application of 6-Aminochrysene to mice induces development of benign skin tumors after 3 months and of skin malignancies after 7 months. Female mice respond earlier than males. Induction of skin tumors is more rapid when 6-Aminochrysene is applied ventrally instead of dorsally. Urinary excretion is about twice as high after skin application than after oral administration. |
6-AMINOCHRYSENE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | GC0500000 |
| HS Code | 29214900 |
6-AMINOCHRYSENE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.11 ml | 20.551 ml | 41.102 ml |
| 5 mM | 0.822 ml | 4.11 ml | 8.22 ml |
| 10 mM | 0.411 ml | 2.055 ml | 4.11 ml |
| 5 mM | 0.082 ml | 0.411 ml | 0.822 ml |
Last Update：2024-01-02 23:10:35
6-AMINOCHRYSENE - Reference Information
| Biological activity | 6-Aminochrysene (6-Aminochrysene) is an aromatic amine compound that can be used in the study of splenomegaly, myeloid leukemia and breast cancer. |
Last Update：2024-04-09 02:00:07
Supplier List
Product Name: 6-Aminochrysene Visit Supplier Webpage Request for quotation
CAS: 2642-98-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 2642-98-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 6-Aminochrysene Visit Supplier Webpage Request for quotation
CAS: 2642-98-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 2642-98-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History