6-Trifluoromethyl-4(1H)-pyrimidinone - Names and Identifiers
6-Trifluoromethyl-4(1H)-pyrimidinone - Physico-chemical Properties
Molecular Formula | C5H3F3N2O
|
Molar Mass | 164.09 |
Density | 1.55±0.1 g/cm3(Predicted) |
Melting Point | 169-171°C(lit.) |
Boling Point | 130.3±50.0 °C(Predicted) |
Flash Point | 32.6°C |
Water Solubility | Solubility in methanol (almost transparency). Slightly soluble in water. |
Vapor Presure | 9.76mmHg at 25°C |
Appearance | White powder |
Color | White |
BRN | 145548 |
pKa | 6.41±0.40(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.484 |
MDL | MFCD00192530 |
6-Trifluoromethyl-4(1H)-pyrimidinone - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
HS Code | 29335990 |
Hazard Class | IRRITANT |
6-Trifluoromethyl-4(1H)-pyrimidinone - Introduction
6-(trifluoromethyl)-4-pyrimidinol, also known as TFP-OH, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: The TFP-OH is white crystal or crystalline powder.
-Solubility: It is soluble in polar organic solvents, such as alcohols, ethers and ketones.
-Stability: It can exist stably under certain conditions, but it is more sensitive to light and heat.
Use:
- TFP-OH can be used as an important reagent in organic synthesis, especially in the synthesis of ribonucleic acid (RNA).
-It can be used to change the chemical properties of nucleotides or other organic molecules, such as introducing protecting groups or functional groups.
Method:
-The preparation method of TFP-OH is relatively simple, and is generally generated by reacting a trifluoromethyl compound with a compound containing a hydroxyl group.
Safety Information:
- TFP-OH dust can cause irritation to the respiratory tract and eyes, so it is necessary to wear appropriate personal protective equipment when handling.
-It may have a certain toxic impact on the environment, so when using and disposing, you need to follow the corresponding safety procedures.
-For TFP-OH specific safety information and risk assessments, refer to their relevant safety data forms or consult a professional.
Last Update:2024-04-09 20:49:11