6-chloro-4-methylpyridine-2-carbonitrile - Names and Identifiers
6-chloro-4-methylpyridine-2-carbonitrile - Physico-chemical Properties
Molecular Formula | C7H5ClN2
|
Molar Mass | 152.58 |
Density | 1.26±0.1 g/cm3(Predicted) |
Boling Point | 283.6±35.0 °C(Predicted) |
Flash Point | 125.3°C |
Vapor Presure | 0.00314mmHg at 25°C |
pKa | -4.97±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.554 |
6-chloro-4-methylpyridine-2-carbonitrile - Introduction
It is an organic compound with the chemical formula C8H7ClN. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: It is a colorless to yellowish crystal.
-Solubility: It has good solubility in common organic solvents.
-Melting point: Its melting point range is 90-92°C.
-Storage stability: The compound should be stored in a dry, cool environment, away from fire and oxidizing agents.
Use:
-can be used as pesticide intermediates, in the preparation of grass and pesticides and other fields have certain applications.
-It can also be used for catalytic reactions in organic synthesis, such as Suzuki-Miyaura coupling reactions.
Method:
The preparation of Lin is generally carried out by the following steps:
1.2-methoxy -5-chloro -4-methyl pyridine is reacted with boron trifluoride (BF3) ether solution to obtain the corresponding 4-methyl pyridine.
2. React 4-methylpyridine with zinc cyanide to obtain pyridine.
Safety Information:
-is an organic cyanide compound, which has certain toxicity and should be used with caution.
-During operation and use, wear appropriate protective gloves and glasses to avoid contact with skin and eyes.
-Avoid inhaling its dust and steam and ensure that it is operated in a well-ventilated environment.
-If contact or inhalation occurs, immediately flush the affected area with plenty of water and seek medical assistance.
Please note that the preparation and use of chemicals should follow relevant safe operating procedures and are best handled by professionals under appropriate laboratory conditions.
Last Update:2024-04-10 22:29:15