6338-55-2
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
CAS: 6338-55-2
Molecular Formula: C6H15NO3
6338-55-2 - Names and Identifiers
| Name | 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL |
| Synonyms | NSC40760 H2N-PEG3-OH (PEO)3-mono-amine 3,6,9-Trioxadecylamine AMINOETHOXY ETHOXY ETHANOL 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL Ethanol, 2-(2-(2-aminoethoxy)ethoxy)- 2-[2-(2-Hydroxyethoxy)ethoxy]ethylamine |
| CAS | 6338-55-2 |
| EINECS | 804-174-6 |
| InChIKey | ASDQMECUMYIVBG-UHFFFAOYSA-N |
6338-55-2 - Physico-chemical Properties
| Molecular Formula | C6H15NO3 |
| Molar Mass | 149.19 |
| Density | 1.0773 g/cm3at 20℃(lit.) |
| Boling Point | 120-130℃ (4 Torr) |
| pKa | 14.36±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.4645 (589.3 nm 20℃ |
| Physical and Chemical Properties | EPA Chemical Information Ethanol, 2-[2-(2-aminoethoxy)ethoxy]- (6338-55-2) |
| Use | 2-(2-(2-aminoethoxy) ethoxy) ethanol can be used as a pharmaceutical and chemical synthetic intermediate. |
6338-55-2 - Risk and Safety
| Risk Codes | R41 - Risk of serious damage to eyes R34 - Causes burns R37/38 - Irritating to respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 2735 |
| WGK Germany | 3 |
| Hazard Class | 8 |
| Packing Group | Ⅱ |
6338-55-2 - Upstream Downstream Industry
6338-55-2 - Nature
| BRN | 1739188 |
Last Update：2024-04-09 20:45:29
6338-55-2 - Uses and synthesis methods
application
2-[2-(2-aminoethoxy) ethoxy] ethanol is an organic synthesis intermediate and pharmaceutical intermediate, which can be used in laboratory research and development synthesis processes and chemical biological research and development processes.
Preparation method
1) preparation of BP103a01: under the protection of nitrogen, add 200mL pyridine to a 1000ml three-mouth bottle, 120 gBP103a00(1.0eq), stir and cool to 0 ℃, add 151.8gTsCl(1.0eq) in batches, stir for 1h, then slowly rise to room temperature, and continue stirring for 3-4h. After the reaction is over, the reaction solution is poured into dilute hydrochloric acid solution of ice, EA is added for extraction, EA layer is washed once with dilute hydrochloric acid, saturated sodium bicarbonate is washed, saturated salt is washed with water, anhydrous Na2SO4 is dried, solvent is evaporated under reduced pressure, and 55g of BP103a01 pure product is obtained by silica gel column chromatography.
2) Preparation of BP103a02(2-[2-(2-aminoethoxy) ethoxy] ethanol): add 55 gBP103a01(1.0eq) and 160mLDMSO to a 1000mL three-mouth bottle, stir evenly, then add NaN323.52g(2.0eq), heat to 50 ℃ for 3 hours, cool to room temperature, pour the reaction liquid into water, extract with EA, combine organic phases, and dry, concentrate to obtain 29.2g of BP103a02 colorless liquid 2-[2-(2-aminoethoxy) ethoxy] ethanol.
Last Update：2024-04-09 22:09:11
Supplier List
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Spot supply
Product Name: Aripiprazole Impurity 71 Visit Supplier Webpage Request for quotationCAS: 6338-55-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 2-[2-(2-Aminoethoxy)Ethoxy]Ethanol Visit Supplier Webpage Request for quotationCAS: 6338-55-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for 6338-55-2
Ethanol, 2-[2-[2-[bis(phenylmethyl)amino]ethoxy]ethoxy]-
2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
Triethylene glycol
2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
Hydroxy-PEG3-Mes
Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate)
2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
Triethylene glycol
2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
Hydroxy-PEG3-Mes
Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate)
Downstream Products for 6338-55-2