65550-79-0

65550-79-0 - Names and Identifiers

Name	2-Bromo-5-chloronicotinic acid
Synonyms	2-Bromo-5-chloronicotinic acid 2-broMo-5-chloropyridine-3-carboxylic acid 3-Pyridinecarboxylic acid, 2-broMo-5-chloro- tert-butyl 3-allyl-3-hydroxyazetidine-106-carboxylate
CAS	65550-79-0
InChI	InChI=1/C6H3BrClNO2/c7-5-4(6(10)11)1-3(8)2-9-5/h1-2H,(H,10,11)

65550-79-0 - Physico-chemical Properties

Molecular Formula	C6H3BrClNO2
Molar Mass	236.45
Density	1.917±0.06 g/cm3(Predicted)
Boling Point	343.1±42.0 °C(Predicted)
pKa	1.75±0.10(Predicted)
Storage Condition	2-8℃
Refractive Index	1.629

65550-79-0 - Introduction

2-Bromo-5-choronicotinic acid is an organic compound with the chemical formula C6H3BrClNO2. The following is a description of the nature, use, method and safety information:

Nature:
-Appearance: Usually a white crystalline solid.
-Melting point: about 135-140°C.
-Solubility: Soluble in water and some organic solvents, such as chloroform and ethanol.
-Chemical properties: 2-Bromo-5-chloronicotinic acid is an aromatic carboxylic acid with acidity and reactivity.

Use:
-Chemical intermediate: 2-Bromo-5-chloronicotinic acid can be used as an intermediate in organic synthesis for the synthesis of other compounds.
-Pesticide: It can be used as a raw material for pesticides or insecticides.

Preparation Method:
The synthesis of 2-Bromo-5-chloronicotinic acid is usually carried out by the following steps:
1.2-chloro -4-nitro pyridine and cuprous bromide are reacted to obtain 2-bromo -4-nitro pyridine.
2. 2-bromo-4-nitropyridine reacts with ammonia to generate 2-bromopyridine.
3. 2-Bromo-5-chloronicotinic acid is obtained by reacting 2-bromopyridine with sodium hypochlorite.

Safety Information:
-2-Bromo-5-choronicotinic acid has low toxicity, but it should still be operated in accordance with laboratory safety procedures.
-Avoid contact with skin, eyes and respiratory tract and wear appropriate protective equipment when using.
-In the process of operation to properly dispose of waste and solution, to avoid pollution to the environment.
-Storage should be sealed and kept away from fire and oxidizing agents.

Last Update：2024-04-10 22:29:15