7-Xylosyl-10-deacetylcephalomannine

7-Xylosyl-10-deacetylcephalomannine - Names and Identifiers

Name	DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)
Synonyms	10-Deacetyl-7-xylosyltaxol B 7-Xylosyl-10-deacetyltaxol B 7-Xylosyl-10-deacetylcephalomannine 10-Deacetylcephalomannine 7-xyloside DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG) Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2...
CAS	90332-64-2

7-Xylosyl-10-deacetylcephalomannine - Physico-chemical Properties

Molecular Formula	C48H59NO17
Molar Mass	921.98
Density	1.43±0.1 g/cm3(Predicted)
Boling Point	1041.3±65.0 °C(Predicted)
pKa	11.26±0.70(Predicted)
Storage Condition	2-8℃

7-Xylosyl-10-deacetylcephalomannine - Introduction

10-deacetyltaxol B(DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)) is a natural compound from the Taxol family.

Nature:
-Appearance: colorless crystal
-Molecular formula: C47H51NO15
-Molecular Weight: 853.92
-Melting Point: 165-167 ° C
-Solubility: Soluble in chloroform, dichloromethane, methanol and other organic solvents

Use:
-Chemical research: As a model compound of natural products, it is used to synthesize various paclitaxel derivatives.
-Anti-tumor drug development: Compounds of The paclitaxel family have anti-tumor activity, and 10-deacetylpaclitaxel B has also been studied as a candidate for anti-tumor drugs.

Method:
10-deacetyltaxol B is usually synthesized from natural Taxol B, and the synthesis process involves a series of chemical conversion steps, including esterification, reduction reaction and glycosidation reaction, etc.

Safety Information:
The safety and toxicity of 10-deacetylpaclitaxel B have not been comprehensively studied and evaluated. Therefore, appropriate safety procedures should be followed when using this compound, and protection should be carried out according to the actual situation. At the same time, the preparation, use and disposal of related compounds should be carried out in accordance with laboratory safety procedures.

Last Update：2024-04-09 21:11:58