90332-64-2 - Names and Identifiers
Name | DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)
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Synonyms | 10-Deacetyl-7-xylosyltaxol B 7-Xylosyl-10-deacetyltaxol B 7-Xylosyl-10-deacetylcephalomannine 10-Deacetylcephalomannine 7-xyloside DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG) Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2...
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CAS | 90332-64-2
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90332-64-2 - Physico-chemical Properties
Molecular Formula | C48H59NO17
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Molar Mass | 921.98 |
Density | 1.43±0.1 g/cm3(Predicted) |
Boling Point | 1041.3±65.0 °C(Predicted) |
pKa | 11.26±0.70(Predicted) |
Storage Condition | 2-8℃ |
90332-64-2 - Introduction
10-deacetyltaxol B(DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)) is a natural compound from the Taxol family.
Nature:
-Appearance: colorless crystal
-Molecular formula: C47H51NO15
-Molecular Weight: 853.92
-Melting Point: 165-167 ° C
-Solubility: Soluble in chloroform, dichloromethane, methanol and other organic solvents
Use:
-Chemical research: As a model compound of natural products, it is used to synthesize various paclitaxel derivatives.
-Anti-tumor drug development: Compounds of The paclitaxel family have anti-tumor activity, and 10-deacetylpaclitaxel B has also been studied as a candidate for anti-tumor drugs.
Method:
10-deacetyltaxol B is usually synthesized from natural Taxol B, and the synthesis process involves a series of chemical conversion steps, including esterification, reduction reaction and glycosidation reaction, etc.
Safety Information:
The safety and toxicity of 10-deacetylpaclitaxel B have not been comprehensively studied and evaluated. Therefore, appropriate safety procedures should be followed when using this compound, and protection should be carried out according to the actual situation. At the same time, the preparation, use and disposal of related compounds should be carried out in accordance with laboratory safety procedures.
Last Update:2024-04-09 21:11:58