73724-40-0
Fmoc-Ala-OSu
CAS: 73724-40-0
Molecular Formula: C22H20N2O6
73724-40-0 - Names and Identifiers
73724-40-0 - Physico-chemical Properties
| Molecular Formula | C22H20N2O6 |
| Molar Mass | 408.4 |
| Density | 1.40±0.1 g/cm3(Predicted) |
| Appearance | Powder |
| Color | Off-white to white |
| pKa | 10.18±0.46(Predicted) |
| Storage Condition | -15°C |
| Sensitive | IRRITANT |
| MDL | MFCD00065613 |
73724-40-0 - Introduction
N-Fmoc-L-alanine N-hydroxysuccinimide ester (Fmoc-Ala-OSu) is an important chemical reagent commonly used in the synthesis of peptide chains. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance is white or off-white solid.
-Stable at room temperature, but sensitive to humidity.
-Soluble in solution in dimethyl sulfoxide (DMSO) or dichloromethane (DCM).
-The chemical structure is Fmoc-protected L-alanine is esterified with hydroxysuccinimide.
Use:
- Fmoc-Ala-OSu alanine residues commonly used in the synthesis of polypeptide or protein sequences.
-As an amino acid protecting group, the amino group of the alanine residue can be protected during synthesis.
-Through the hydroxysuccinimide ester reaction, Fmoc-Ala-OSu can be chain extended with other amino acid residues.
Preparation Method:
-The preparation of Fmoc-Ala-OSu is mainly prepared by reacting Fmoc-L-alanine with hydroxysuccinimide ester under alkaline conditions.
Safety Information:
- Fmoc-Ala-OSu is a chemical reagent that needs to be operated in a laboratory environment.
-Follow relevant safety practices when handling, including wearing appropriate protective equipment, such as lab gloves and glasses.
-Do not inhale, swallow or contact with skin.
-Should be stored in a dry, low temperature, away from direct sunlight.
Nature:
-Appearance is white or off-white solid.
-Stable at room temperature, but sensitive to humidity.
-Soluble in solution in dimethyl sulfoxide (DMSO) or dichloromethane (DCM).
-The chemical structure is Fmoc-protected L-alanine is esterified with hydroxysuccinimide.
Use:
- Fmoc-Ala-OSu alanine residues commonly used in the synthesis of polypeptide or protein sequences.
-As an amino acid protecting group, the amino group of the alanine residue can be protected during synthesis.
-Through the hydroxysuccinimide ester reaction, Fmoc-Ala-OSu can be chain extended with other amino acid residues.
Preparation Method:
-The preparation of Fmoc-Ala-OSu is mainly prepared by reacting Fmoc-L-alanine with hydroxysuccinimide ester under alkaline conditions.
Safety Information:
- Fmoc-Ala-OSu is a chemical reagent that needs to be operated in a laboratory environment.
-Follow relevant safety practices when handling, including wearing appropriate protective equipment, such as lab gloves and glasses.
-Do not inhale, swallow or contact with skin.
-Should be stored in a dry, low temperature, away from direct sunlight.
Last Update：2024-04-09 02:00:56
