84624-28-2
H-Lys(Fmoc)-OH
CAS: 84624-28-2
Molecular Formula: C21H24N2O4
84624-28-2 - Names and Identifiers
| Name | H-Lys(Fmoc)-OH |
| Synonyms | H-Lys(Fmoc)-OH H-LYS(FMOC)-OH LYSINE(FMOC)-OH N6-Fmoc-L-lysine N'-Fmoc-L-lysine H-L-Lys(Fmoc)-OH N'-Fmoc-L-Lysine N-EPSILON-FMOC-L-LYSINE N'-(9-Fluorenylmethyloxycarbonyl)-L-lysine N-EPSILON-9-FLUORENYLMETHOXYCARBONYL-L-LYSINE N6-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine N-EPSILON-(9-FLUORENYLMETHOXYCARBONYL)-L-LYSINE (2S)-2-ammonio-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}hexanoate |
| CAS | 84624-28-2 |
| InChI | InChI=1/C21H24N2O4/c22-19(20(24)25)11-5-6-12-23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25)/t19-/m0/s1 |
84624-28-2 - Physico-chemical Properties
| Molecular Formula | C21H24N2O4 |
| Molar Mass | 368.43 |
| Density | 1.245 |
| Melting Point | 209-210 °C |
| Boling Point | 609.9±55.0 °C(Predicted) |
| Flash Point | 322.6°C |
| Vapor Presure | 9.96E-16mmHg at 25°C |
| pKa | 2.53±0.24(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
| Refractive Index | 1.6 |
84624-28-2 - Introduction
H-Lys(Fmoc)-OH(H-Lys(Fmoc)-OH) is an amino acid protector commonly used in solid-phase synthesis. It has the following properties:
-Chemical properties: H-Lys(Fmoc)-OH is a white solid, insoluble in water, soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
-Functional group: The compound contains an amino group (-NH2) at one end and a carboxylic acid (-COOH) at the other end. The amino group is a side chain functional group of lysine.
- Fmoc protecting group: The amino group of H-Lys(Fmoc)-OH has an Fmoc protecting group, which can protect the amino group during the synthesis to prevent the occurrence of side reactions.
H-Lys(Fmoc)-OH is mainly used in solid phase synthesis to protect amino groups in the synthesis of peptides and proteins. It can form a polypeptide chain by linking with other amino acid monomers, and remove the Fmoc protecting group by a deprotection reaction under basic conditions after the reaction.
A common method for preparing H-Lys(Fmoc)-OH is by reacting lysine with Fmoc-OSu to form the reaction intermediate Fmoc-L-lysine-Osu, which is further reacted with N-protected lysine to form the target product H-Lys(Fmoc)-OH.
For safety information, please note the following:
- H-Lys(Fmoc)-OH may be irritating to the skin, eyes and respiratory system. Wear appropriate protective equipment such as gloves, goggles and masks.
-When using H-Lys(Fmoc)-OH for synthesis reactions, the safe operation of relevant chemicals should be followed.
-Store H-Lys(Fmoc)-OH in a dry, low-temperature, dark place, and away from flammables and oxidants.
This information is for reference only. Please consult the relevant literature and chemical safety data sheets carefully before use.
-Chemical properties: H-Lys(Fmoc)-OH is a white solid, insoluble in water, soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
-Functional group: The compound contains an amino group (-NH2) at one end and a carboxylic acid (-COOH) at the other end. The amino group is a side chain functional group of lysine.
- Fmoc protecting group: The amino group of H-Lys(Fmoc)-OH has an Fmoc protecting group, which can protect the amino group during the synthesis to prevent the occurrence of side reactions.
H-Lys(Fmoc)-OH is mainly used in solid phase synthesis to protect amino groups in the synthesis of peptides and proteins. It can form a polypeptide chain by linking with other amino acid monomers, and remove the Fmoc protecting group by a deprotection reaction under basic conditions after the reaction.
A common method for preparing H-Lys(Fmoc)-OH is by reacting lysine with Fmoc-OSu to form the reaction intermediate Fmoc-L-lysine-Osu, which is further reacted with N-protected lysine to form the target product H-Lys(Fmoc)-OH.
For safety information, please note the following:
- H-Lys(Fmoc)-OH may be irritating to the skin, eyes and respiratory system. Wear appropriate protective equipment such as gloves, goggles and masks.
-When using H-Lys(Fmoc)-OH for synthesis reactions, the safe operation of relevant chemicals should be followed.
-Store H-Lys(Fmoc)-OH in a dry, low-temperature, dark place, and away from flammables and oxidants.
This information is for reference only. Please consult the relevant literature and chemical safety data sheets carefully before use.
Last Update：2024-04-09 15:18:00
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Spot supply
Product Name: N-Epsilon-Fmoc-L-Lysine Visit Supplier Webpage Request for quotationCAS: 84624-28-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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