85862-77-7 - Names and Identifiers
85862-77-7 - Physico-chemical Properties
| Molecular Formula | C10H13N3
|
| Molar Mass | 175.24 |
85862-77-7 - Upstream Downstream Industry
85862-77-7 - Introduction
1-azido-4-butylbenzene(1-azido-4-butylbenzene) is a compound with the chemical formula C10H13N3. The following is an introduction to its properties, uses, preparation methods and safety information:
1. Nature:
-Appearance: 1-azido-4-butylbenzene is a colorless to light yellow liquid or solid.
-Melting point: about 17-19 degrees Celsius.
-Boiling point: About 150-152 degrees Celsius.
-Density: about 0.991 g/mL.
-Soluble: It can be dissolved in ether, dichloromethane and alcohol, but almost insoluble in water.
2. Use:
- 1-azido-4-butylbenzene can be used for "click" reactions in organic synthesis, such as reacting with alkynes in "click" reactions to generate 1,2,3-triazoles similar to trifluoroethers.
-It can also be used as a precursor of complexes, such as ligands in metal complexes.
3. Preparation method:
The preparation methods of 1-azido-4-butylbenzene are as follows:
-Reaction by Grignard reagent: First use Grignard reagent (synthesized from bromobutane and sodium) to convert butyl bromide into butyl Grignard reagent, and then react with phenylimine to obtain 1-azido-4-butylbenzene.
-Through nitrosyl reaction: First, 4-butylbenzensulfonyl chloride is converted into 4-butylbenzensulfonyl azide through nitrosyl reaction, and then it is converted into 1-azido-4-butylbenzene through reduction reaction.
4. Safety Information:
- 1-azido-4-butylbenzene is harmful and should be avoided from direct skin contact, inhalation or ingestion.
-Appropriate personal protective measures should be taken during operation, such as wearing gloves, masks and protective glasses.
-In case of contact, flush the affected area with clean water. Seek medical help if you feel unwell.
Last Update：2024-04-10 22:29:15