910309-46-5
N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine
CAS: 910309-46-5
Molecular Formula: C13H18BrNO3
910309-46-5 - Names and Identifiers
910309-46-5 - Physico-chemical Properties
| Molecular Formula | C13H18BrNO3 |
| Molar Mass | 316.19 |
910309-46-5 - Introduction
N-Boc-2-(3-bromophene)-2-hydroxyethanamine, chemical formula C13H18BrNO3, is an organic compound.
Nature:
N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine is a solid with a white or off-white crystalline appearance. It is stable at ambient temperature and soluble in most organic solvents such as ethanol, dimethylformamide and dichloromethane. Its melting point ranges from 70-75 degrees Celsius.
Use:
N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine is an important intermediate in organic synthesis, which is commonly used in substitution reactions and condensation reactions in organic synthesis. It can be used to prepare a variety of biologically active compounds, such as drugs, pesticides and functional materials.
Method:
The synthesis of N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine is usually achieved by reacting in a dehydroacetic acid environment. First, 3-bromobenzoic acid is reacted with tert-butyl dicarboxylic acid (also known as Boc2O) to obtain N-Boc-3 bromobenzoic acid, which is then subjected to a condensation reaction with 2-hydroxyethylamine, and after appropriate treatment and purification, the target product is obtained.
Safety Information:
the specific safety information of N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine has not been publicly reported, but as an organic synthesis intermediate, it should abide by the laboratory's safe operation procedures and avoid contact with skin, eyes and inhalation of its dust or vapor. During use and storage, care should be taken to prevent ignition and avoid contact with strong oxidants. If necessary, individual protective measures should be followed, such as wearing protective glasses, gloves and protective clothing. If an accident occurs, seek medical attention immediately.
Nature:
N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine is a solid with a white or off-white crystalline appearance. It is stable at ambient temperature and soluble in most organic solvents such as ethanol, dimethylformamide and dichloromethane. Its melting point ranges from 70-75 degrees Celsius.
Use:
N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine is an important intermediate in organic synthesis, which is commonly used in substitution reactions and condensation reactions in organic synthesis. It can be used to prepare a variety of biologically active compounds, such as drugs, pesticides and functional materials.
Method:
The synthesis of N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine is usually achieved by reacting in a dehydroacetic acid environment. First, 3-bromobenzoic acid is reacted with tert-butyl dicarboxylic acid (also known as Boc2O) to obtain N-Boc-3 bromobenzoic acid, which is then subjected to a condensation reaction with 2-hydroxyethylamine, and after appropriate treatment and purification, the target product is obtained.
Safety Information:
the specific safety information of N-Boc-2-(3-bromophenyl)-2-hydroxyethanamine has not been publicly reported, but as an organic synthesis intermediate, it should abide by the laboratory's safe operation procedures and avoid contact with skin, eyes and inhalation of its dust or vapor. During use and storage, care should be taken to prevent ignition and avoid contact with strong oxidants. If necessary, individual protective measures should be followed, such as wearing protective glasses, gloves and protective clothing. If an accident occurs, seek medical attention immediately.
Last Update：2024-04-09 21:01:54
