915086-32-7

915086-32-7 - Names and Identifiers

Name	4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile
Synonyms	Thiohydantoin androgen receptor antagonist 4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolid... 4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile Benzonitrile, 4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl]-2-(trifluoromethyl)- 4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
CAS	915086-32-7

915086-32-7 - Physico-chemical Properties

Molecular Formula	C19H14F3N3O2S
Molar Mass	405.39
Density	1.52±0.1 g/cm3 (20 ºC 760 Torr)
Boling Point	548.7±60.0 °C(Predicted)
pKa	9.01±0.30(Predicted)
Storage Condition	2-8°C(protect from light)

915086-32-7 - Upstream Downstream Industry

Raw Materials

Propanenitrile,2-[(4-hydroxyphenyl)amino]-2-methyl-
4-isothiocyanato-2-(trifluoroMethyl)benzonitrile

915086-32-7 - Introduction

4-(3-(4-hydroxyphenyl)-4, phenyl)-2-(trifluoroMethyl)benzonitrile is an organic compound commonly abbreviated as THIOM. Its nature, use, method and safety information are as follows:

Nature:
-Appearance: Colorless to light yellow crystal powder.
-Molecular formula: C17H11F3N2OS2.
-Relative molecular mass: 406.4g/mol.
-Melting point: 128-133 ° C.
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, insoluble in water.

Use:
- THIOM has certain biological activity and can be used in drug research and development.
-It can also be used as a reagent in organic synthesis, such as imidazolidine stabilizers and reagents, and novel catalysts.

Method:
The preparation of THIOM is usually obtained by chemical synthesis methods. Specifically, the benzonitrile derivative is first synthesized, and then the final product is obtained through a two-step reaction. Some organic reagents and solvents are commonly used in the reaction, and the experimental conditions and reaction control need to be paid attention.

Safety Information:
-When handling this compound, you need to follow Good Laboratory Practices and wear suitable protective equipment, such as gloves and glasses.
- THIOM is an organic compound that may be toxic to humans. During the operation, care should be taken to avoid contact with skin, eyes and inhalation of gas.
-When accidentally touching or swallowing the compound, wash the affected area immediately and seek medical help.
-In addition, avoid contact with oxidants, high temperatures and open flames during use and storage. The correct storage method is to place it in an airtight container and store it in a cool, dry place.

Last Update：2024-04-09 20:52:54