945599-35-9
1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 4-iodo-, 1,1-diMethylethyl ester
CAS: 945599-35-9
Molecular Formula: C11H12IN3O2
945599-35-9 - Names and Identifiers
945599-35-9 - Physico-chemical Properties
| Molecular Formula | C11H12IN3O2 |
| Molar Mass | 345.14 |
945599-35-9 - Introduction
1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 4-iodo-, 1,1-diMethylethyl ester is an organic compound with the chemical formula C13H15IN4O2.
Nature:
-Appearance: Often white to light yellow crystalline powder.
-Melting point: about 110-112°C.
-Solubility: Soluble in some organic solvents (such as methanol, dimethyl sulfoxide and dichloromethane), insoluble in water.
Use:
- 1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 4-iodo-, 1,1-diMethylethyl ester is an important organic synthesis intermediate, commonly used in organic synthesis chemical reactions.
-It can be used as a key intermediate in drug synthesis, such as for the synthesis of various indole and pyrazole compounds.
Method:
The synthesis of 1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 4-iodo-, 1,1-diMethylethyl ester usually includes the following steps:
1. the azaindazole and acid are reacted to generate the corresponding acid salt.
2. The acid salt reacts with iodine to obtain the corresponding iodide.
3. The iodide is reacted with a Boc-protected amino compound.
4. Finally, the resulting product is subjected to a deprotection reaction to obtain the final compound.
Safety Information:
Because organic compounds are often used in experiments, it is necessary to follow the general safety measures of organic chemistry experiments to ensure that the experimental operation is carried out under well-ventilated conditions. Also, the safety data for this compound is limited, please refer to the accurate safety instructions when using or handling this compound, and use personal protective equipment (such as protective gloves, goggles and laboratory coats) for protection.
Nature:
-Appearance: Often white to light yellow crystalline powder.
-Melting point: about 110-112°C.
-Solubility: Soluble in some organic solvents (such as methanol, dimethyl sulfoxide and dichloromethane), insoluble in water.
Use:
- 1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 4-iodo-, 1,1-diMethylethyl ester is an important organic synthesis intermediate, commonly used in organic synthesis chemical reactions.
-It can be used as a key intermediate in drug synthesis, such as for the synthesis of various indole and pyrazole compounds.
Method:
The synthesis of 1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 4-iodo-, 1,1-diMethylethyl ester usually includes the following steps:
1. the azaindazole and acid are reacted to generate the corresponding acid salt.
2. The acid salt reacts with iodine to obtain the corresponding iodide.
3. The iodide is reacted with a Boc-protected amino compound.
4. Finally, the resulting product is subjected to a deprotection reaction to obtain the final compound.
Safety Information:
Because organic compounds are often used in experiments, it is necessary to follow the general safety measures of organic chemistry experiments to ensure that the experimental operation is carried out under well-ventilated conditions. Also, the safety data for this compound is limited, please refer to the accurate safety instructions when using or handling this compound, and use personal protective equipment (such as protective gloves, goggles and laboratory coats) for protection.
Last Update：2024-04-09 21:11:58
