AMINOETHOXY ETHOXY ETHANOL
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
CAS: 6338-55-2
Molecular Formula: C6H15NO3
AMINOETHOXY ETHOXY ETHANOL - Names and Identifiers
| Name | 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL |
| Synonyms | NSC40760 H2N-PEG3-OH (PEO)3-mono-amine 3,6,9-Trioxadecylamine AMINOETHOXY ETHOXY ETHANOL 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL Ethanol, 2-(2-(2-aminoethoxy)ethoxy)- 2-[2-(2-Hydroxyethoxy)ethoxy]ethylamine |
| CAS | 6338-55-2 |
| EINECS | 804-174-6 |
| InChIKey | ASDQMECUMYIVBG-UHFFFAOYSA-N |
AMINOETHOXY ETHOXY ETHANOL - Physico-chemical Properties
| Molecular Formula | C6H15NO3 |
| Molar Mass | 149.19 |
| Density | 1.0773 g/cm3at 20℃(lit.) |
| Boling Point | 120-130℃ (4 Torr) |
| pKa | 14.36±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.4645 (589.3 nm 20℃ |
| Physical and Chemical Properties | EPA Chemical Information Ethanol, 2-[2-(2-aminoethoxy)ethoxy]- (6338-55-2) |
| Use | 2-(2-(2-aminoethoxy) ethoxy) ethanol can be used as a pharmaceutical and chemical synthetic intermediate. |
AMINOETHOXY ETHOXY ETHANOL - Risk and Safety
| Risk Codes | R41 - Risk of serious damage to eyes R34 - Causes burns R37/38 - Irritating to respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 2735 |
| WGK Germany | 3 |
| Hazard Class | 8 |
| Packing Group | Ⅱ |
AMINOETHOXY ETHOXY ETHANOL - Upstream Downstream Industry
AMINOETHOXY ETHOXY ETHANOL - Nature
| BRN | 1739188 |
Last Update：2024-04-09 20:45:29
AMINOETHOXY ETHOXY ETHANOL - Uses and synthesis methods
application
2-[2-(2-aminoethoxy) ethoxy] ethanol is an organic synthesis intermediate and pharmaceutical intermediate, which can be used in laboratory research and development synthesis processes and chemical biological research and development processes.
Preparation method
1) preparation of BP103a01: under the protection of nitrogen, add 200mL pyridine to a 1000ml three-mouth bottle, 120 gBP103a00(1.0eq), stir and cool to 0 ℃, add 151.8gTsCl(1.0eq) in batches, stir for 1h, then slowly rise to room temperature, and continue stirring for 3-4h. After the reaction is over, the reaction solution is poured into dilute hydrochloric acid solution of ice, EA is added for extraction, EA layer is washed once with dilute hydrochloric acid, saturated sodium bicarbonate is washed, saturated salt is washed with water, anhydrous Na2SO4 is dried, solvent is evaporated under reduced pressure, and 55g of BP103a01 pure product is obtained by silica gel column chromatography.
2) Preparation of BP103a02(2-[2-(2-aminoethoxy) ethoxy] ethanol): add 55 gBP103a01(1.0eq) and 160mLDMSO to a 1000mL three-mouth bottle, stir evenly, then add NaN323.52g(2.0eq), heat to 50 ℃ for 3 hours, cool to room temperature, pour the reaction liquid into water, extract with EA, combine organic phases, and dry, concentrate to obtain 29.2g of BP103a02 colorless liquid 2-[2-(2-aminoethoxy) ethoxy] ethanol.
Last Update：2024-04-09 22:09:11
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Product Name: PROTAC Linker 35 Visit Supplier Webpage Request for quotationCAS: 6338-55-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 2-(2-(2-Aminoethoxy)ethoxy)ethanol Visit Supplier Webpage Request for quotationCAS: 6338-55-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-(2-(2-Aminoethoxy)ethoxy)ethanol Visit Supplier Webpage Request for quotationCAS: 6338-55-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 2-[2-(2-Aminoethoxy)Ethoxy]Ethanol Visit Supplier Webpage Request for quotationCAS: 6338-55-2
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View History
AMINOETHOXY ETHOXY ETHANOL
Curcubit[7]uril
487029-68-5
环己烷-1,2-二羧酸二异壬酯DINCH
2,3-Dimethyl-2,3-dinitrobutane
VAROX DBPH-50
4-苯基偶氮-1,3-苯二胺盐酸盐
t-Butyl 1-Benzhydryl-3-azetidinylcarbamate
十甲基苯氟酸酯
ETHYL 3-METHYLBUTANOATE
Curcubit[7]uril
487029-68-5
环己烷-1,2-二羧酸二异壬酯DINCH
2,3-Dimethyl-2,3-dinitrobutane
VAROX DBPH-50
4-苯基偶氮-1,3-苯二胺盐酸盐
t-Butyl 1-Benzhydryl-3-azetidinylcarbamate
十甲基苯氟酸酯
ETHYL 3-METHYLBUTANOATE
Raw Materials for AMINOETHOXY ETHOXY ETHANOL
Ethanol, 2-[2-(2-bromoethoxy)ethoxy]-
Triethylene glycol
2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
Hydroxy-PEG3-Mes
Triethylene glycol
2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
Hydroxy-PEG3-Mes
Downstream Products for AMINOETHOXY ETHOXY ETHANOL