BTS
BTS
CAS: 1576-37-0
Molecular Formula: C14H15NO2S
BTS - Names and Identifiers
| Name | BTS |
| Synonyms | BTS N-Tosylbenzylamine LABOTEST-BB LT00786416 n-benzyl-p-toluenesulfonamid N-BENZYL-P-TOLUENESULFONAMIDE N-BENZYL-P-TOLUENESULPHONAMIDE N-BENZYL-4-METHYL-BENZENESULFONAMIDE 4-methyl-n-(phenylmethyl)-benzenesulfonamid 4-METHYL-N-(PHENYLMETHYL)BENZENESULFONAMIDE |
| CAS | 1576-37-0 |
| InChI | InChI=1/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3 |
BTS - Physico-chemical Properties
| Molecular Formula | C14H15NO2S |
| Molar Mass | 261.34 |
| Density | 1.204±0.06 g/cm3(Predicted) |
| Melting Point | 115 °C |
| Boling Point | 419.1±48.0 °C(Predicted) |
| Flash Point | 207.3°C |
| Solubility | Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly) |
| Vapor Presure | 3.12E-07mmHg at 25°C |
| Appearance | White crystalline solid |
| Color | White to Off-White |
| pKa | 11.54±0.30(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Light Sensitive |
| Refractive Index | 1.589 |
| MDL | MFCD00159328 |
| Physical and Chemical Properties | RTECS:XT5490000 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| In vitro study | BTS (2-12 μM) inhibits the Ca 2+ -stimulated ATPase activity of myosin S1 in the absence of actin, with an IC 50 of ~5 µM. BTS (2-20 μM) reversibly inhibits the gliding motility rate of heavy meromyosin (HMM). BTS (100 μM) releases myosin from actin in the presence of ADP. BTS (0-20 μM) reversibly inhibits isometric Ca 2+ -activated tension in skinned skeletal muscle fibres from rabbit and frog, with IC 50 s of ~3 µM and 1 µM, respectively. |
BTS - Risk and Safety
| RTECS | XT5490000 |
BTS - Reference Information
| Biological activity | BTS (N-Benzyl-p-toluenesulfonamide) is an effective and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity. The IC50 value of actin and Ca2 + stimulated myosin S1 ATPase is about 5 µM. BTS can specifically inhibit the contraction of skeletal muscle rapid fibers. |
| target | IC50: ~ 5 µM (skeletal muscle myosin II S1 ATPase) |
| use | A potent inhibitor of skeletal muscle Ca2 -stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin holmium interaction with F-actin. Doesnot affect platelet myosin II. |
Last Update：2024-04-09 21:32:04
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Product Name: N-Tosylbenzylamine Visit Supplier Webpage Request for quotationCAS: 1576-37-0
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Mobile: 18021002903
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