N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine MedChemExpress (MCE)

Product Name	BTS
Synonyms	BTS N-Tosylbenzylamine LABOTEST-BB LT00786416 n-benzyl-p-toluenesulfonamid N-BENZYL-P-TOLUENESULFONAMIDE N-BENZYL-P-TOLUENESULPHONAMIDE N-BENZYL-4-METHYL-BENZENESULFONAMIDE Synonyms BTS N-Tosylbenzylamine LABOTEST-BB LT00786416 n-benzyl-p-toluenesulfonamid N-BENZYL-P-TOLUENESULFONAMIDE N-BENZYL-P-TOLUENESULPHONAMIDE N-BENZYL-4-METHYL-BENZENESULFONAMIDE 4-methyl-n-(phenylmethyl)-benzenesulfonamid 4-METHYL-N-(PHENYLMETHYL)BENZENESULFONAMIDE
CAS	1576-37-0
EINECS
Chemical Formula	C14H15NO2S
Molecular Weight	261.34
inchi	InChI=1/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3
Package	10 mM * 1 mL;1 g;5 g
Price	Email to quote
Descriptions	BTS BTS MedChemExpress (MCE) HY-16690 1576-37-0 N-Benzyl-p-toluenesulfonamide Descriptions BTS BTS MedChemExpress (MCE) HY-16690 1576-37-0 N-Benzyl-p-toluenesulfonamide N-Tosylbenzylamine 99.74% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC50s of ~5 μM for actin- and Ca2+-stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers. BTS (2-12 μM) inhibits the Ca2+-stimulated ATPase activity of myosin S1 in the absence of actin, with an IC50 of ~5 μM[1]. BTS (2-20 μM) reversibly inhibits the gliding motility rate of heavy meromyosin (HMM)[1]. BTS (100 μM) releases myosin from actin in the presence of ADP[1]. BTS (0-20 μM) reversibly inhibits isometric Ca2+-activated tension in skinned skeletal muscle fibres from rabbit and frog, with IC50s of ~3 μM and 1 μM, respectively[1]. IC50: ~5 µM (skeletal muscle myosin II S1 ATPase) In Vitro BTS (2-12 μM) inhibits the Ca2+-stimulated ATPase activity of myosin S1 in the absence of actin, with an IC50 of ~5 μM[1]. BTS (2-20 μM) reversibly inhibits the gliding motility rate of heavy meromyosin (HMM)[1]. BTS (100 μM) releases myosin from actin in the presence of ADP[1]. BTS (0-20 μM) reversibly inhibits isometric Ca2+-activated tension in skinned skeletal muscle fibres from rabbit and frog, with IC50s of ~3 μM and 1 μM, respectively[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> BTS Related Antibodies \| \| \| \| \| \| \| \| \| \| [1]. Cheung A, et al. A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol. 2002 Jan 4(1):83-8. [Content Brief] [2]. Shaw MA, et, al. Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide. Biochemistry. 2003 May 27 42(20):6128-35. [Content Brief]
Last Update	2025-04-01 14:45:47

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