Boc-b-HoAla(2-naphthyl)-OH - Names and Identifiers
Boc-b-HoAla(2-naphthyl)-OH - Physico-chemical Properties
Molecular Formula | C19H23NO4
|
Molar Mass | 329.4 |
Density | 1.179 |
Boling Point | 527.9±43.0 °C(Predicted) |
pKa | 4.42±0.10(Predicted) |
Storage Condition | 2-8°C |
Boc-b-HoAla(2-naphthyl)-OH - Risk and Safety
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
Hazard Class | IRRITANT |
Boc-b-HoAla(2-naphthyl)-OH - Introduction
Boc-(S)-3-Amino-4-(2-napthyl)-butyric acid is an organic compound with the chemical formula C22H25NO4 and a molecular weight of 367.45. It is a white crystalline solid.
its nature:
-melting point: about 75-77 ℃
-Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide and methanol, but it is difficult to dissolve in water.
Its purpose:
Boc-(S)-3-Amino-4-(2-napthyl)-butyric acid is a commonly used amine protecting reagent, in which the Boc group (tert-butoxycarbonyl group) can effectively protect the amino group. The compound is commonly used in the field of organic synthesis for the synthesis of peptides, drugs and bioactive molecules.
Preparation Method:
Boc-(S)-3-Amino-4-(2-naphthyl)-butyric acid can be prepared by reacting S-acetyl -3-amino -4-(2-naphthyl) butyric acid with tert-butyl hydroxybenzoate. The specific step is to first react S-acetyl -3-amino -4-(2-naphthyl) butyric acid with diethyl carbonate to obtain the product, and then react with tert-butyl hydroxybenzoate to form the target compound.
Safety Information:
Boc-(S)-3-Amino-4-(2-napthyl)-butyric acid is relatively safe under routine operations, but as an organic compound, it still needs to comply with laboratory safety practices. Avoid inhalation, skin contact and ingestion. Operate in a well-ventilated area and wear appropriate personal protective equipment such as lab gloves and goggles. For accidental contact or ingestion, seek medical attention promptly.
Last Update:2024-04-09 02:00:49