N-BETA-T-BUTOXYCARBONYL-L-HOMO(2-NAPHTHYL)ALANINE

N-BETA-T-BUTOXYCARBONYL-L-HOMO(2-NAPHTHYL)ALANINE - Names and Identifiers

Name	Boc-(S)-3-Amino-4-(2-naphthyl)-butyric acid
Synonyms	Boc-b-HoAla(2-naphthyl)-OH boc-4-(2-naphthyl)-l-β-homoalanine BOC-(S)-3-AMINO-4-(2-NAPHTHYL)BUTANOIC ACID BOC-(S)-2-AMINO-4-(2-NAPHTHYL)-BUTYRIC ACID Boc-(S)-3-amino-4-(2-naphenyl)butanoic acid Boc-(S)-3-Amino-4-(2-naphthyl)-butyric acid N-BETA-T-BUTOXYCARBONYL-L-HOMO(2-NAPHTHYL)ALANINE Boc-β-2-Homonal-OH, Boc-4-(2-naphthyl)-L-β-homoalanine N-T-BUTOXYCARBONYL-(S)-3-AMINO-4-(2-NAPHTHYL)BUTANOIC ACID
CAS	219297-11-7

N-BETA-T-BUTOXYCARBONYL-L-HOMO(2-NAPHTHYL)ALANINE - Physico-chemical Properties

Molecular Formula	C19H23NO4
Molar Mass	329.4
Density	1.179
Boling Point	527.9±43.0 °C(Predicted)
pKa	4.42±0.10(Predicted)
Storage Condition	2-8°C

N-BETA-T-BUTOXYCARBONYL-L-HOMO(2-NAPHTHYL)ALANINE - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	10
Hazard Class	IRRITANT

N-BETA-T-BUTOXYCARBONYL-L-HOMO(2-NAPHTHYL)ALANINE - Introduction

Boc-(S)-3-Amino-4-(2-napthyl)-butyric acid is an organic compound with the chemical formula C22H25NO4 and a molecular weight of 367.45. It is a white crystalline solid.

its nature:
-melting point: about 75-77 ℃
-Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide and methanol, but it is difficult to dissolve in water.

Its purpose:
Boc-(S)-3-Amino-4-(2-napthyl)-butyric acid is a commonly used amine protecting reagent, in which the Boc group (tert-butoxycarbonyl group) can effectively protect the amino group. The compound is commonly used in the field of organic synthesis for the synthesis of peptides, drugs and bioactive molecules.

Preparation Method:
Boc-(S)-3-Amino-4-(2-naphthyl)-butyric acid can be prepared by reacting S-acetyl -3-amino -4-(2-naphthyl) butyric acid with tert-butyl hydroxybenzoate. The specific step is to first react S-acetyl -3-amino -4-(2-naphthyl) butyric acid with diethyl carbonate to obtain the product, and then react with tert-butyl hydroxybenzoate to form the target compound.

Safety Information:
Boc-(S)-3-Amino-4-(2-napthyl)-butyric acid is relatively safe under routine operations, but as an organic compound, it still needs to comply with laboratory safety practices. Avoid inhalation, skin contact and ingestion. Operate in a well-ventilated area and wear appropriate personal protective equipment such as lab gloves and goggles. For accidental contact or ingestion, seek medical attention promptly.

Last Update：2024-04-09 02:00:49