Molecular Formula | C19H24N6O2 |
Molar Mass | 368.43 |
Solubility | DMSO: ≥ 33 mg/mL |
Storage Condition | -20℃ |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.714 ml | 13.571 ml | 27.142 ml |
5 mM | 0.543 ml | 2.714 ml | 5.428 ml |
10 mM | 0.271 ml | 1.357 ml | 2.714 ml |
5 mM | 0.054 ml | 0.271 ml | 0.543 ml |
biological activity | DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has Anti tuberculosis effect. |
Target | DprE1 |
Animal Model: | BALB/c Mice |
Dosage: | 100 mg/kg |
Administration: | Oral |
Result: | Had t 1/2 of 0.9 hours and C max of 70 μM. |