DprE1-IN-2 - Names and Identifiers
DprE1-IN-2 - Physico-chemical Properties
Molecular Formula | C19H24N6O2
|
Molar Mass | 368.43 |
Solubility | DMSO: ≥ 33 mg/mL |
Storage Condition | -20℃ |
DprE1-IN-2 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.714 ml | 13.571 ml | 27.142 ml |
5 mM | 0.543 ml | 2.714 ml | 5.428 ml |
10 mM | 0.271 ml | 1.357 ml | 2.714 ml |
5 mM | 0.054 ml | 0.271 ml | 0.543 ml |
Last Update:2024-01-02 23:10:35
DprE1-IN-2 - Reference Information
biological activity | DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has Anti tuberculosis effect. |
Target | DprE1 |
Animal Model:
| BALB/c Mice |
Dosage:
| 100 mg/kg |
Administration:
| Oral |
Result:
| Had t 1/2 of 0.9 hours and C max of 70 μM. |
Last Update:2024-04-09 22:09:11