D-ADENOSINE
Adenosine
CAS: 58-61-7
Molecular Formula: C10H13N5O4
D-ADENOSINE - Names and Identifiers
| Name | Adenosine |
| Synonyms | AR Adenosine D-ADENOSINE ADENINENUCLEOSIDE adenosine free base 9-BETA-D-RIBOFURANOSYLADENINE ADENOSINE extrapure for biochemistry 9-alpha-D-lyxofuranosyl-9H-purin-6-amine 6-Amino-9-(beta-D-ribofuranosyl)9H-purine Adenine riboside, Adenine-9-beta-ribofuranoside 9-β-D-Ribofuranosyladenine, Adenine riboside, Adenine-9-β-D-ribofuranoside (2R,3R,4S,5R)-2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL |
| CAS | 58-61-7 |
| EINECS | 200-389-9 |
| InChI | InChI=1/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6+,7+,10+/m1/s1 |
| InChIKey | OIRDTQYFTABQOQ-KQYNXXCUSA-N |
D-ADENOSINE - Physico-chemical Properties
| Molecular Formula | C10H13N5O4 |
| Molar Mass | 267.24 |
| Density | 1.3382 (rough estimate) |
| Melting Point | 234-236 °C (lit.) |
| Boling Point | 410.43°C (rough estimate) |
| Specific Rotation(α) | D11 -61.7° (c = 0.706 in water); 9D -58.2° (c = 0.658 in water) |
| Flash Point | 362.8°C |
| Water Solubility | Soluble in water, ammonium hydroxide and dimethyl sulfoxide. Insoluble in ethanol. |
| Solubility | Soluble in water, insoluble in alcohol |
| Vapor Presure | 3.26E-19mmHg at 25°C |
| Appearance | White crystal |
| Color | White |
| Merck | 14,153 |
| BRN | 93029 |
| pKa | 3.6, 12.4(at 25℃) |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | 1.7610 (estimate) |
| MDL | MFCD00005752 |
| Physical and Chemical Properties | Colorless needle-like crystals of hemihydrate. |
| Use | For the manufacture of ATP, adenosine Arabinoside, coenzyme A, etc |
D-ADENOSINE - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 2 |
| RTECS | AU7175000 |
| FLUKA BRAND F CODES | 10-23 |
| TSCA | Yes |
| HS Code | 29389090 |
| Toxicity | LD50 oral in mouse: > 20gm/kg |
D-ADENOSINE - Nature
Open Data Verified Data
- This product is white crystalline powder, odorless, bitter. The melting point was 234-235 °c. Soluble in water, almost insoluble in ether, chloroform and ethanol.
- This product can directly enter the myocardium to be phosphorylated into adenosine, participate in myocardial energy metabolism, dilate coronary vessels and increase coronary blood flow. Since it is easily destroyed by adenosine deaminase in the body, the effect is not long-lasting. It also has a peripheral vasodilator effect, which is weaker than the coronary vasodilator effect, and also has a transient hypotensive effect. In addition, it also slightly attenuated the role of myocardial contractility.
Last Update：2024-01-02 23:10:35
D-ADENOSINE - Use
Open Data Verified Data
- treatment of angina, myocardial infarction, coronary insufficiency, arteriosclerosis, essential hypertension, cerebrovascular disorders, stroke sequelae, progressive muscle atrophy.
- use, usage and dosage of oral, daily 60~90mg, divided into 3 times to take, mild Daily 30mg, severe daily 12 0mg.
Last Update：2022-01-01 11:12:34
D-ADENOSINE - Safety
Open Data Verified Data
atrioventricular block and acute myocardial infarction patients disabled.
Last Update：2022-01-01 11:12:34
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