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Difenoconazole E.C.

Difenoconazole

CAS: 119446-68-3

Molecular Formula: C19H17Cl2N3O3

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Difenoconazole E.C. - Names and Identifiers

Name Difenoconazole
Synonyms Score
DIVIDEND
Dividend
Cga169374
Difenoconazol
DIFENOCONAZOL
Difenoconazole
DIFENOCONAZOLE
Difenoconazole E.C.
difenoconazole (bsi,draft e-iso)
1h-1,2,4-Triazole,1-((2-(2-Chloro-4-(4-Chlorophenoxy)Phenyl)-4-Methyl-1,3-Diox
3-Chloro-4-4-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-y14-chlorophenylether
1H-1,2,4-Triazole, 1-2-2-chloro-4-(4-chlorophenoxy)phenyl-4-methyl-1,3-dioxolan-2-ylmethyl-
1-[2-[4-(4-chlorophenoxy)-2-chlorophenyl]-4-methyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole
4-Triazole,1-((2-(2-Chloro-4-(4-Chlorophenoxy)Phenyl)-4-Methyl-1,3-Dioxolan-2-Yl)Methyl)-1h-2
1-({2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole
1-((2-(2-Chloro-4-(4-Chlorophenoxy)Phenyl)-4-Methyl-1,3-Dioxolan-2-Yl)Methyl)-1h-1,2,4-Triazole
1-((2-(2-chloro-4-(4-chlorophenoxy)phenyl)-4-methyl-1,3-dioxolan-2-yl)methyl)-1h-1,2,4-triazole
Cis,Trans-3-Chloro-4-[4-Methyl-2-(1h-1,2,4-Triazol-1-Ylmethyl)-1,3-Dioxolan-2-Yl]Phenyl 4-Chlorophenyl Ether
Cis,Trans-3-Chloro-4-[4-Methyl-2-(1h-1,2,4-Triazole-1-Methyl)-1,3-Dioxylpentane-2-] Phenyl-4-Chlorophenyl Ether
CAS 119446-68-3
InChI InChI=1/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3

Difenoconazole E.C. - Physico-chemical Properties

Molecular FormulaC19H17Cl2N3O3
Molar Mass406.26
Density1.4916 (rough estimate)
Melting Point76°C
Boling Point220°C
Flash Point284.6°C
Water Solubility3.3 mg/L (20 ºC)
Solubility Water soluble 3.3 mg/L (20°C)
Vapor Presure3.3 x l0-8 Pa (25 °C)
AppearanceColorless solid
Merck13,3160
BRN9073356
pKa2.94±0.12(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,2-8°C
Refractive Index1.6140 (estimate)
MDLMFCD00144119
Physical and Chemical PropertiesMelting Point: 76°C
Boiling Point: 220°C
storage conditions: 0-6°C
water solubility: 3.3 mg/L (20°C)
Merck:13,3160
colorless solid
UseOxadiazole is a triazole fungicide with systemic absorption, which is a sterol demethylation inhibitor and has a wide bactericidal spectrum. It belongs to triazole fungicide, with internal absorption and broad bactericidal spectrum, and is a sterol demethylation inhibitor. Broad bactericidal spectrum for foliar treatment or seed treatment

Difenoconazole E.C. - Risk and Safety

Risk CodesR22 - Harmful if swallowed
R41 - Risk of serious damage to eyes
R43 - May cause sensitization by skin contact
R50 - Very Toxic to aquatic organisms
R20/22 - Harmful by inhalation and if swallowed.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. 
UN IDsUN 3077 9 / PGIII
WGK Germany3
RTECSXZ4380000
ToxicityLD50 in rats (mg/kg): 1453 orally; in rabbits: >2010 dermally (Ruess)

Difenoconazole E.C. - Reference

Reference
Show more
1. Zhang Min, Zhao Chi Na, Han Fei, et al. Screening of 5 Sterol Biosynthesis Inhibitors (SBIs) antifungal drugs against 9 plant pathogenic fungi [J]. Journal of Pesticide 2020.
2. Pan Jialiang, Yao Hanwen, Geng Zheng, et al. Synergistic effect of matrine on fungicide against pecan dry rot [J]. Journal of Northeast Forestry University, 2018, 46(001):101-104.

Difenoconazole E.C. - Introduction

Water soluble 3.3mg/L(20 ℃).
Last Update：2022-10-16 17:12:31

Difenoconazole E.C. - Reference Information

NIST chemical information Information provided by: webbook.nist.gov (external link)
EPA chemical information Information provided by: ofmpub.epa.gov (external link)
Introduction Difenoconazole, also known as oxoconazole, trade name "Shigao", belongs to triazole fungicides and is a sterol demethylation inhibitor. It has the characteristics of high efficiency, broad-spectrum, low toxicity, and low dosage. It is an excellent variety of triazole fungicides. It has strong absorption and inhibits the biosynthesis of ergosterol in bacterial cells, thereby destroying the cell membrane structure and function of pathogenic bacteria, used in fruit trees, vegetables, wheat, potatoes, beans, melons and other crops, and has a good protection and treatment effect on vegetables, melons and fruits and other fungal diseases. The characteristics of "three nos" (no pollution of the environment, no pollution of agricultural products, no killing of natural enemies), it is an ideal fungicide for preventing and controlling citrus scab, spotted leaf disease and other crop resistant diseases in my country and even in the world.
mechanism of action difenoconazole water dispersible granules are beige to brown fine granules. Difenoconazole has a strong inhibitory effect on the spore formation of plant pathogens, and can inhibit the maturation of conidia, thereby controlling the further development of the disease. The mode of action of fenoconazole is to interfere with the C14 demethylation of pathogenic bacteria cells and inhibit the biosynthesis of ergosterol, so that the sterol stays in the cell membrane, damages the physiological function of the membrane, and leads to the death of fungi. Difenoconazole bactericidal spectrum
features ① internal absorption and conduction, broad bactericidal spectrum difenoconazole is a triazole fungicide, which is an efficient, safe, low toxic and broad spectrum fungicide, which can be absorbed by plants and has strong infiltration effect. within 2 hours after application, it is absorbed by crops and has the characteristics of upward conduction, it can protect the newborn young leaves, flowers, and fruits from germs. It can be treated with one medicine and has good control effect on various fungal diseases. It can effectively prevent and treat scab, leaf spot, powdery mildew and rust of vegetables, and has both preventive and therapeutic effects. (2) Rain-resistant scouring, drug effect lasting adhesion on the leaf surface of the agent rain-resistant scouring, from the leaf volatilization is very little, even under high temperature conditions also show a more durable bactericidal activity, than the general fungicide lasting 3~4 days. ③The dosage form is advanced, and the crop safety water dispersible granule consists of active ingredients, dispersants, wetting agents, disintegrating agents, defoamers, adhesives, anti-caking agents and other additives, through micro-refinement, spray drying and other processes Granulation. The water can be quickly disintegrated and dispersed, forming a high suspension dispersion system, no dust influence, and safe for users and the environment. It does not contain organic solvents and is safe for recommended crops. (4) difenoconazole can be mixed with propiconazole, azoxystrobin and other fungicides for the production of compound fungicides.
Synthesis method Using m-dichlorobenzene as raw material, through acylation, etherification, bromination, cyclization and condensation reactions, difenoconazole is finally synthesized. Fig. 1 shows the synthesis route of difenoconazole
use it has excellent control effect on grape, peanut, kernel fruit, potato, wheat, vegetable and other crops. (2016-01-13)
oxazole is a triazole fungicide, with systemic, is a sterol demethylation inhibitor, and has a broad bactericidal spectrum.
oxetherazole is a triazole fungicide, with systemic, is a sterol demethylation inhibitor, and has a broad bactericidal spectrum. It is a triazole fungicide with systemic and broad bactericidal spectrum. It is a sterol demethylation inhibitor. Wide sterilization spectrum, used for foliar treatment or seed treatment
Wide sterilization spectrum, used for foliar treatment or seed treatment
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update：2024-04-10 22:29:15
Difenoconazole E.C.
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Mobile: +86-17551318830
SKYRUN INDUSTRIAL CO.,LTD
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Mobile: +86-18621343501
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Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Difenoconazole Request for quotation
CAS: 119446-68-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Difenoconazole Visit Supplier Webpage Request for quotation
CAS: 119446-68-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Difenoconazole Visit Supplier Webpage Request for quotation
CAS: 119446-68-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
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