FMOC-2-CYANO-D-PHENYLALANINE

FMOC-2-CYANO-D-PHENYLALANINE - Names and Identifiers

Name	2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
Synonyms	fmoc-D-2-cyanophenylalanine Fmoc-D-2-Cyanophenylalanine Fmoc-2-Cyano-D-phenylalanine (R)-Fmoc-2-amino-(2-cyanophenyl)propanoic acid (9H-Fluoren-9-yl)MethOxy]Carbonyl D-2-Cyanophe 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine 2-Cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine 2-Cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine L-phenylalanine, 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- D-Phenylalanine, 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(2-cyanophenyl)propanoic acid (2S)-3-(2-Cyanophenyl)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (2R)-3-(2-cyanophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS	401620-74-4
InChI	InChI=1/C25H20N2O4/c26-14-17-8-2-1-7-16(17)13-23(24(28)29)27-25(30)31-15-22-20-11-5-3-9-18(20)19-10-4-6-12-21(19)22/h1-12,22-23H,13,15H2,(H,27,30)(H,28,29)/t23-/m0/s1

FMOC-2-CYANO-D-PHENYLALANINE - Physico-chemical Properties

Molecular Formula	C25H20N2O4
Molar Mass	412.44
Density	1.35g/cm³
Boling Point	666°C at 760 mmHg
Flash Point	356.6°C
Vapor Presure	1.2E-18mmHg at 25°C
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.672

FMOC-2-CYANO-D-PHENYLALANINE - Risk and Safety

WGK Germany

FMOC-2-CYANO-D-PHENYLALANINE - Introduction

2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine is an organic compound with the chemical formula C30H23N3O4. It is a cyano protecting reagent containing D-2-cyanophenylalanine.

2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine is commonly used in solid-phase synthesis as a protective reagent for amino acids. It protects the reactive groups in the amino acid by adding a protecting group Fmoc on the side chain of the amino acid to prevent uncontrolled reactions during the reaction. This ensures that the desired chemical reaction takes place only at the specified site.

The method of preparing 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine is similar to general amino acid synthesis. Usually, starting from L-phenylalanine, the 2-cyano group is introduced by chemical reaction, and then the side chain of the amino acid is protected with Fmoc. The specific synthesis method requires the specific operation of the organic chemistry laboratory.

Regarding safety information, since 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine is an organic compound, you need to pay attention to protective measures when using it. Contact with eyes, skin or inhalation may be harmful to health. Therefore, appropriate personal protective equipment should be worn during operation, such as laboratory gloves and eye protection glasses. At the same time, attention should be paid to operating in a well-ventilated place to avoid inhaling harmful vapors.

Last Update：2024-04-10 22:29:15