FMOC-GLYCINE-OPFP
pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate
CAS: 86060-85-7
Molecular Formula: C23H14F5NO4
FMOC-GLYCINE-OPFP - Names and Identifiers
| Name | pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate |
| Synonyms | Fmoc-Gly-Opfp FMOC-GLY-OPFP FMOC-GLYCINE-OPFP FMOC-GLYCINE PENTAFLUOROPHENYL ESTER N-FMOC-GLYCINE PENTAFLUOROPHENYL ESTER N-(9-fluorenylmethoxycarbonyl)glycine pentafluorophenyl pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate NALPHA-9-Fluorenylmethoxycarbonylglycine pentafluorophenyl ester |
| CAS | 86060-85-7 |
| InChI | InChI=1/C23H14F5NO4/c24-17-18(25)20(27)22(21(28)19(17)26)33-16(30)9-29-23(31)32-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,29,31) |
FMOC-GLYCINE-OPFP - Physico-chemical Properties
| Molecular Formula | C23H14F5NO4 |
| Molar Mass | 463.35 |
| Density | 1.4222 (estimate) |
| Melting Point | 159-160 °C |
| Boling Point | 570.9°C at 760 mmHg |
| Flash Point | 299.1°C |
| Vapor Presure | 4.8E-13mmHg at 25°C |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.568 |
FMOC-GLYCINE-OPFP - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
FMOC-GLYCINE-OPFP - Introduction
pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate is an organic compound with the chemical formula C20H16F5NO4. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White solid
-Molecular weight: 431.34g/mol
-melting point: about 126-129 ℃
-Soluble: Slightly soluble in ethanol, dichloromethane and chloroform
Use:
pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate is a reagent that temporarily protects amino acids and is commonly used in peptide synthesis and drug development. It can protect the hydroxyl or amine group in the amino acid to prevent unnecessary reaction or degradation, and can be reduced or hydrolyzed when necessary.
Preparation Method:
The method for preparing pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate is usually to obtain the target product by reacting fluorenmethanol, pentafluorobenzoic acid and glycine through acid catalysis and the action of an activator.
Safety Information:
pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate is generally stable and relatively safe under normal conditions of use, the following matters still need to be paid attention:
-Avoid contact with skin and eyes, and rinse with plenty of water immediately after contact.
-Use good laboratory practices to avoid inhalation of dust or splashes.
-should be in a well ventilated place to operate, avoid inhalation of vapor.
-Follow relevant chemical safety regulations for handling and storage.
-For detailed safety information and handling methods, please refer to the relevant safety data sheet.
Nature:
-Appearance: White solid
-Molecular weight: 431.34g/mol
-melting point: about 126-129 ℃
-Soluble: Slightly soluble in ethanol, dichloromethane and chloroform
Use:
pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate is a reagent that temporarily protects amino acids and is commonly used in peptide synthesis and drug development. It can protect the hydroxyl or amine group in the amino acid to prevent unnecessary reaction or degradation, and can be reduced or hydrolyzed when necessary.
Preparation Method:
The method for preparing pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate is usually to obtain the target product by reacting fluorenmethanol, pentafluorobenzoic acid and glycine through acid catalysis and the action of an activator.
Safety Information:
pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycinate is generally stable and relatively safe under normal conditions of use, the following matters still need to be paid attention:
-Avoid contact with skin and eyes, and rinse with plenty of water immediately after contact.
-Use good laboratory practices to avoid inhalation of dust or splashes.
-should be in a well ventilated place to operate, avoid inhalation of vapor.
-Follow relevant chemical safety regulations for handling and storage.
-For detailed safety information and handling methods, please refer to the relevant safety data sheet.
Last Update：2024-04-09 19:05:52
