FMOC-PHE(O-CL)-OH

FMOC-PHE(O-CL)-OH - Names and Identifiers

Name	FMOC-L-2-Chlorophe
Synonyms	FMOC-PHE(O-CL)-OH FMOC-PHE(2-CL)-OH Fmoc-Phe(2-Cl)-OH FMOC-L-2-Chlorophe RARECHEM BK PT 0003 FMOC-L-PHE(2-CL)-OH FMOC-O-CHLORO-L-PHE-OH Fmoc-L-2-Chlorophenylalanine Fmoc-2-Chloro-L-phenylalanine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-CHLORO-L-PHENYLALANINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2-CHLORO-PHENYLALANINE (S)-3-(2-CHLORO-PHENYL)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID
CAS	198560-41-7
InChI	InChI=1/C24H20ClNO4/c25-21-12-6-1-7-15(21)13-22(23(27)28)26-24(29)30-14-20-18-10-4-2-8-16(18)17-9-3-5-11-19(17)20/h1-12,20,22H,13-14H2,(H,26,29)(H,27,28)/t22-/m1/s1

FMOC-PHE(O-CL)-OH - Physico-chemical Properties

Molecular Formula	C24H20ClNO4
Molar Mass	421.87
Density	1.337±0.06 g/cm3(Predicted)
Melting Point	158°C
Boling Point	640.9±55.0 °C(Predicted)
Specific Rotation(α)	-46 º (c=1,EtOAc)
Flash Point	341.4°C
Vapor Presure	2.64E-17mmHg at 25°C
Appearance	Powder
Color	White
pKa	3.72±0.11(Predicted)
Storage Condition	2-8°C
Refractive Index	1.637
Physical and Chemical Properties	Storage Conditions: 2-8 ℃ WGK Germany:3

FMOC-PHE(O-CL)-OH - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Class	IRRITANT

FMOC-PHE(O-CL)-OH - Introduction

FMOC-L-2-Chlorophe is an organic compound with the chemical formula C25H18ClNO4, which is widely used in the field of chemistry.

Nature:
FMOC-L-2-Chlorophe is a white to light yellow crystalline solid with some solubility. It is a derivative of an FMOC protected amino acid, and the FMOC group can be removed by acid treatment, thereby exposing the free amino acid.

Use:
FMOC-L-2-Chlorophe are mostly used in peptide synthesis to synthesize a portion of the peptide chain. It can be used as an amino acid protective agent to protect the α-amino group of amino acid and some functional groups on the side chain to avoid unnecessary reactions in the process of peptide chain synthesis. In addition, it can also be used in the synthesis of antimicrobial peptides, functional peptides and drug molecules.

Method:
The preparation of FMOC-L-2-Chlorophe is generally obtained by reacting phenylalanine with dibenzoyl chloride. Specific preparation methods can be found in the literature of organic synthesis.

Safety Information:
FMOC-L-2-Chlorophe there is no obvious danger under regular operation, it is still necessary to pay attention to personal protection and laboratory safety. During operation, please take care to avoid inhalation, ingestion and contact with skin or eyes. Use with suitable protective equipment such as gloves, goggles and an exhaust system outside the laboratory. At the same time, waste should be properly stored and disposed of, in accordance with relevant laws and regulations.

Last Update：2024-04-09 21:11:58