N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2-CHLORO-PHENYLALANINE
FMOC-L-2-Chlorophe
CAS: 198560-41-7
Molecular Formula: C24H20ClNO4
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2-CHLORO-PHENYLALANINE - Names and Identifiers
| Name | FMOC-L-2-Chlorophe |
| Synonyms | FMOC-PHE(O-CL)-OH FMOC-PHE(2-CL)-OH Fmoc-Phe(2-Cl)-OH FMOC-L-2-Chlorophe RARECHEM BK PT 0003 FMOC-L-PHE(2-CL)-OH FMOC-O-CHLORO-L-PHE-OH Fmoc-L-2-Chlorophenylalanine Fmoc-2-Chloro-L-phenylalanine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-CHLORO-L-PHENYLALANINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2-CHLORO-PHENYLALANINE (S)-3-(2-CHLORO-PHENYL)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID |
| CAS | 198560-41-7 |
| InChI | InChI=1/C24H20ClNO4/c25-21-12-6-1-7-15(21)13-22(23(27)28)26-24(29)30-14-20-18-10-4-2-8-16(18)17-9-3-5-11-19(17)20/h1-12,20,22H,13-14H2,(H,26,29)(H,27,28)/t22-/m1/s1 |
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2-CHLORO-PHENYLALANINE - Physico-chemical Properties
| Molecular Formula | C24H20ClNO4 |
| Molar Mass | 421.87 |
| Density | 1.337±0.06 g/cm3(Predicted) |
| Melting Point | 158°C |
| Boling Point | 640.9±55.0 °C(Predicted) |
| Specific Rotation(α) | -46 º (c=1,EtOAc) |
| Flash Point | 341.4°C |
| Vapor Presure | 2.64E-17mmHg at 25°C |
| Appearance | Powder |
| Color | White |
| pKa | 3.72±0.11(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.637 |
| Physical and Chemical Properties | Storage Conditions: 2-8 ℃ WGK Germany:3 |
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2-CHLORO-PHENYLALANINE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2-CHLORO-PHENYLALANINE - Introduction
FMOC-L-2-Chlorophe is an organic compound with the chemical formula C25H18ClNO4, which is widely used in the field of chemistry.
Nature:
FMOC-L-2-Chlorophe is a white to light yellow crystalline solid with some solubility. It is a derivative of an FMOC protected amino acid, and the FMOC group can be removed by acid treatment, thereby exposing the free amino acid.
Use:
FMOC-L-2-Chlorophe are mostly used in peptide synthesis to synthesize a portion of the peptide chain. It can be used as an amino acid protective agent to protect the α-amino group of amino acid and some functional groups on the side chain to avoid unnecessary reactions in the process of peptide chain synthesis. In addition, it can also be used in the synthesis of antimicrobial peptides, functional peptides and drug molecules.
Method:
The preparation of FMOC-L-2-Chlorophe is generally obtained by reacting phenylalanine with dibenzoyl chloride. Specific preparation methods can be found in the literature of organic synthesis.
Safety Information:
FMOC-L-2-Chlorophe there is no obvious danger under regular operation, it is still necessary to pay attention to personal protection and laboratory safety. During operation, please take care to avoid inhalation, ingestion and contact with skin or eyes. Use with suitable protective equipment such as gloves, goggles and an exhaust system outside the laboratory. At the same time, waste should be properly stored and disposed of, in accordance with relevant laws and regulations.
Nature:
FMOC-L-2-Chlorophe is a white to light yellow crystalline solid with some solubility. It is a derivative of an FMOC protected amino acid, and the FMOC group can be removed by acid treatment, thereby exposing the free amino acid.
Use:
FMOC-L-2-Chlorophe are mostly used in peptide synthesis to synthesize a portion of the peptide chain. It can be used as an amino acid protective agent to protect the α-amino group of amino acid and some functional groups on the side chain to avoid unnecessary reactions in the process of peptide chain synthesis. In addition, it can also be used in the synthesis of antimicrobial peptides, functional peptides and drug molecules.
Method:
The preparation of FMOC-L-2-Chlorophe is generally obtained by reacting phenylalanine with dibenzoyl chloride. Specific preparation methods can be found in the literature of organic synthesis.
Safety Information:
FMOC-L-2-Chlorophe there is no obvious danger under regular operation, it is still necessary to pay attention to personal protection and laboratory safety. During operation, please take care to avoid inhalation, ingestion and contact with skin or eyes. Use with suitable protective equipment such as gloves, goggles and an exhaust system outside the laboratory. At the same time, waste should be properly stored and disposed of, in accordance with relevant laws and regulations.
Last Update：2024-04-09 21:11:58
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CAS: 198560-41-7
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CAS: 198560-41-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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